4636-45-7Relevant academic research and scientific papers
Efficient synthesis of novel polyfunctionalised 4,5′-bithiazol- 4′-ol derivatives
Arcadi, Antonio,Attanasi, Orazio A.,Filippone, Paolino,Perrulli, Francesca R.,Rossi, Elisabetta,Santeusanio, Stefania
, p. 2681 - 2684 (2007/10/03)
2-Thiazolin-4-one derivatives, obtained by reaction of tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-bromoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5′-bithiazol-4′-ol derivatives.
