4643-33-8

Upstream product

• 7154-66-7 2-bromobenzoic acid chloride 
• 314284-07-6 2-iodo-N-(naphthalen-1-yl)benzamide 
• 134-32-7 1-amino-naphthalene 
• 63295-62-5 2-bromo-N-(naphthalen-1-yl)benzamide 
• 609-67-6 2-Iodobenzoyl chloride 
• 74881-59-7 2-Iodo-N-methyl-N-naphthalen-1-yl-benzamide 
• 74881-58-6 2-bromo-N-methyl-N-(1-naphthyl)benzamide 
• 86-56-6 N,N-dimethyl-1-naphthalenamine 
• 98-88-4 benzoyl chloride 

Relevant academic research and scientific papers

KMnO4-mediated oxidative C[sbnd]N bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO4-mediated oxidative C[sbnd]N bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.

Electrochemical Reactions. Part 23. Intramolecular Radical Substitution during the Reduction of 2-Halogeno-N-methyl-N-naphthylbenzamides

Phenyl radical intermediates formed by the reductive cleavage of the carbon-halogen bond in 2-halogeno-N-methyl-N-(1-naphthyl)benzamides undergo intramolecular substitution to give N-methyl-2-(1-naphthyl)benzamide, and no N-methylbenzophenanthridone is formed.Reduction of 2-halogeno-N-methyl-N-(2-naphthyl)benzamides gives N-methyl-2-(2-naphthyl)benzamide, N-methylbenzophenanthridone, and N-methylbenzophenanthridone.These results complete our comparison of this electrochemical reaction with related radical Pschorr cyclisations.Further reduction of these initial reaction products occurs that only qualitative conclusions can be drawn from the product yields.