465-29-2

Usage

Uses

Used in Polymer Industry:
DL-Camphorquinone is used as a photoinitiator for initiating the polymerization process when exposed to light. This application is crucial in the production of various polymer-based materials, as it allows for the controlled formation of polymers under specific conditions.
Used in Dentistry:
In dentistry, DL-Camphorquinone is used as a component in light-cured dental fillings and restorative materials. It aids in the hardening process, ensuring that the dental materials set and adhere properly to the tooth structure. This application is essential for providing durable and long-lasting dental restorations.
Safety Precautions:
Due to its potential to cause skin and eye irritation, as well as the risk of harm from prolonged inhalation, DL-Camphorquinone must be handled with care. It is recommended to use gloves and eye protection when working with this substance to minimize the risk of adverse effects.

Upstream product

• 76-22-2 Camphor 
• 7519-74-6 thiocamphor 
• 17697-12-0 benzeneseleninic anhydride 
• 95589-30-3 (1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one 
• 79532-63-1 1-(1-Ethoxy-3,7,7-trimethyl-2-oxo-bicyclo<2.2.1>heptyl)-4-phenyl-1,2,4-triazolidin-3,5-dion 
• 63988-02-3 2-phenylselenocamphor 
• 14487-70-8 3-diazocamphor 
• 464-48-2 (1S)-camphor 
• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 53702-18-4 (+/-)-epicamphor 
• 73333-63-8 Trifluoro-methanesulfonic acid (1R,4S)-4,7,7-trimethyl-3-oxo-bicyclo[2.2.1]hept-2-yl ester 
• 13837-85-9 1,7,7-trimethylbicyclo[2.2.1]heptane-exo,exo-2,3-diol 
• 14487-70-8 3-diazocamphor 
• 100-47-0 benzonitrile 

Downstream Products

• 595-29-9 camphoric anhydride 
• 15210-83-0 2,2,3-trimethyl-4-oxo-cyclohexanecarboxylic acid 
• 71681-63-5 3-o-tolylimino-bornan-2-one 
• 116865-63-5 (+/-)-3-((Ξ)-3-bromo-phenylimino)-bornan-2-one 
• 71681-69-1 (+/-)-3-((Ξ)-4-bromo-phenylimino)-bornan-2-one 
• 117122-83-5 (+/-)-3-((Ξ)-2-bromo-phenylimino)-bornan-2-one 
• 110463-08-6 (+/-)-3-(3-ethoxy-phenylimino)-bornan-2-one 
• 10373-81-6 3-hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 91900-73-1 m-menth-3⁽⁸⁾-ene-2,6-dione 
• 13837-85-9 1,7,7-trimethylbicyclo[2.2.1]heptane-exo,exo-2,3-diol 
• 3278-94-2 homocamphorquinoline 
• 21488-68-6 (1R)-3exo-hydroxy-bornan-2-one 
• 10373-79-2 DL-3-endo-(4-Methyl-benzyl)-3-exo-hydroxy-bornan-2-on 
• 101980-80-7 1,2,2-trimethylcyclopentyl p-methylbenzyl ketone 

Relevant academic research and scientific papers

Novel synthetic method of camphorquinone

The invention relates to a novel synthetic method of camphorquinone, which is a method for preparing camphorquinone from camphor in the presence of a catalyst. The invention further provides a methodfor preparing camphorquinone, which can effectively reduce the toxicity of the used catalyst and reflect the harm to the environment, and ensures a high yield of the reaction while simplifying the process flow. According to the method, clean energy microwave irradiation instead of conventional energy is utilized, so that the pollution of the reaction to the environment is greatly reduced while thereaction yield is ensured, and the purpose of green chemistry is met.

Selectively polymerizable compositions and methods of use in vivo

Otologic materials and methods are provided. For example, a cell-adhesive, biodegradable hydrogel scaffold loaded with time-released drugs for repairing chronic tympanic membrane perforations is disclosed, methods of making same and administering same are provided. This hydrogel may promote vascular in-growth and epithelial cell growth of the tympanic membrane with the purpose of closing the perforation and providing a barrier between the external and middle ear. The hydrogel is initially a liquid polymer that only gels upon exposure to specific conditions, such as exposure to light. This scaffold may simultaneously induce repair of the tympanic membrane while preventing or alleviating middle ear infection, thus filling a void in current tympanic membrane perforation therapies.

Method for producing camphorquinone by taking byproduct generated in camphor synthesis process as raw material

The invention provides a method for producing camphorquinone by taking a byproduct generated in the camphor synthesis process as a raw material, belonging to the technical field of organic synthesis.The byproduct 3-camphene ester generated in the synthesis process of camphor is used as a starting material to prepare high-purity camphorquinone through refining, saponification, dehydrogenation, condensation, hydrolysis and recrystallization steps. The method has the beneficial effects that the value of the byproduct generated in the camphor synthesis process is used, industrial wastes are reduced, wastes are changed into valuables, environmental pressure is reduced, a brand-new path for the synthesis of the camphorquinone is provided, no heavy metals are used in all process steps, truly nontoxic chemical synthesis of the camphorquinone is realized, and the method is an economic and environment-friendly production process.

Selectivity of the complexation reactions of four regioisomeric methylcamphorquinoxaline ligands with gold(III): X-ray, NMR and DFT investigations

Reported are the synthesis, spectral and structural characteristics of new quinoxaline-related regioisomeric ligands L1-L4 (1,x,11,11-tetramethyl-1,2,3,4-tetrahydro-1,4-methanophenazine, x = 7, 8, 9 and 6, respectively) and their mononuclear Au(III) complexes (1-4). Fusion of the camphor moiety to the quinoxaline core made two N-atoms of quinoxaline nonequivalent while the introduction of a methyl-substituent at positions 6-9 enabled a tuning of coordination properties of L1-L4. Gold(III) complexes 1-4 and ligands L1-L4 have been studied in detailed by 1D and 2D NMR and the structures of 1-4 have been determined by X-ray crystallography. The results of these analyses revealed a regiospecific coordination of Au(III) to the sterically less hindered N-5 atom (spatially close to the non-substituted bridgehead carbon) of L1-L3, and to N-10 (spatially close to the methyl-substituted bridgehead carbon) of L4. The results of DFT calculations shed light on disparate coordination modes of L1-L4 toward the AuCl3 fragment and explain formation of single coordination products in high yield.

A phenanthroline-derived ligand and its complexation with Pd(II): From ligand design, synthesis and Pd(II) complexes structures to its application

A novel phenanthroline-derived bis-opened-triazine ligand for selective complexation with Pd(ii) over 19 typical metals from HNO3 media was designed based on cavity modulation strategy. Structures of the three species of the Pd(ii) complexes of with the ligand were elucidated by 1H NMR titration isothermal titration calorimetry (ITC) and density functional theory (DFT) studies. ITC test and binding energy calculations demonstrated that the asymmetrical 1:1 Pd(ii)-ligand complex with a monodentate nitrate anion was the most stable among these three species of the Pd(ii) complexes. The excellent kinetics of Pd(ii) extraction with the ligand is due to its optimal conformation completely ready for metal ligation. The enhanced special extraction selectivity and fast extraction rate towards Pd(ii) achieved by the phenanthroline-derived ligand demonstrated that the effective separation of some radionuclides with smaller radius in HLW through cavity modulation strategy is a feasible approach.

SELECTIVELY POLYMERIZABLE COMPOSITIONS AND METHODS OF USE IN VIVO

Otologic materials and methods are provided. For example, a cell-adhesive, biodegradable hydrogel scaffold loaded with time-released drugs for repairing chronic tympanic membrane perforations is disclosed, methods of making same and administering same are provided. This hydrogel may promote vascular in-growth and epithelial cell growth of the tympanic membrane with the purpose of closing the perforation and providing a barrier between the external and middle ear. The hydrogel is initially a liquid polymer that only gels upon exposure to specific conditions, such as exposure to light. This scaffold may simultaneously induce repair of the tympanic membrane while preventing or alleviating middle ear infection, thus filling a void in current tympanic membrane perforation therapies.

METHOD FOR MANUFACTURING ESTER

The present invention relates to a method for manufacturing an ester from a ketone or an aldehyde, which is a reactive substrate, by a Baeyer-Villiger oxidation reaction using hydrogen peroxide, and in this method, as a catalyst, M(BAr4)n, which is a metal borate, is used (M represents an alkali metal or an alkaline earth metal; Ar represents an aryl; and n is the same number as the valence of M). For example, when cyclohexanone was used as the reactive substrate, and Sr[B(3,5-CF3C6H3)4]2 was used as the catalyst, ε-caprolactone was obtained at an isolated yield of 82%.

Efficient synthesis of camphorquinone from camphor

In this study, we discussed an efficient approach for the synthesis of camphorquinone from camphor by the continuous reaction of bromination and oxidation. The oxidation of 3-bromocamphor was catalyzed by Fe-porphyrins with air. The catalytic activity of iron-metallated functional porphyrins was investigated under optimization conditions. The results showed that this method was a milder alternative to the reported methods, with a simple, greener procedure in which the advantages were the utilization of air as the oxidant and the use of metalloporphyrins as catalysts. Copyright Taylor & Francis Group, LLC.

An environment friendly preparation of 3-bromocamphor and camphorquinone

The bromination of camphor has been carried out on a multi-gram scale by a mixture of KBr and KBrO3 in the presence of acid or with HBr/NaBr - H+ and H2O2/oxone as the oxidant. The 3-bromocamphor is then efficiently converted to camphorquinone by an improved oxidation protocol using DMSO and sodium carbonate of tetrabutyl ammonium iodide.

Oxidative cleavage of vicinal diols: IBX can do what Dess-Martin periodinane (DMP) can

A study was conducted to demonstrate the similarity of reactivity between o-iodoxybenzoic acid (IBX), an oxidative agent of vicinal diols and Des-Martin periodinane (DMP). The study examined IBX-mediated oxidative cleavage of tert,tert-1,2-diols and discovered pathways that favored fragmentation of sec,sec-1,2-diols, which produce non-cleavage products. It was observed that IBX can be employed to perform oxidative cleavage of 1,2-diols similar to DMP by simple variation of solvent and temperature. It was also observed that protonation of 10-1-4 species of diols may suppress the nucleophilic attack, leading to the production of ketol to achieve oxidative cleavage of sec,sec-1,2-diols that yield non-cleavage products with IBX in DMSO. TFA was used as a significant source of protons and a better solvent of IBX to conduct protonation of diols. A variety of sec,sec,tert,tert and sec,tert syn-1,2-diols underwent oxidative cleavage effectively, using TFA as a solvent.