4651-52-9

Basic information

• Product Name: ergost-5-en-3-yl acetate
• CAS NO: 4651-52-9
• Molecular Formula: C₃₀H₅₀O₂
• Molecular Weight: 442.7168
• Mol File: 4651-52-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 502.2°C at 760 mmHg
• Flash Point: 254.4°C
• Density: 0.99g/cm³
• Vapor Pressure: 3.24E-10mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: ergost-5-en-3-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ergost-5-en-3-yl acetate(4651-52-9)
• EPA Substance Registry System: ergost-5-en-3-yl acetate(4651-52-9)

Safety Data

• Hazardous Substances Data: 4651-52-9(Hazardous Substances Data)

Upstream product

• 139403-47-7 campesterol 
• 108-24-7 acetic anhydride 
• 100568-99-8 (S)-1-bromo-3,4-dimethylpentane 
• 30540-29-5 butanoic acid, 2,3-dimethyl-, methyl ester 
• 30540-31-9 1-bromo-2,3-dimethyl-butane 
• 30656-60-1 (S)-4,5-dimethylhexanoic acid 
• 14287-61-7 2,3-dimethylbutyric acid 
• 19550-30-2 2,3-dimethylbutanol 
• 15019-29-1 3β-Methoxy-24(S)-methyl-Δ⁵-cholesten-22-on 
• 15019-30-4 3β-Methoxy-(24S)-methylcholest-5-en-(22R)-ol 
• 15019-26-8 (R)-2,3-dimethyl-butyric acid methyl ester 
• 102543-65-7 3β-Methoxy-Δ⁵-bisnor-cholen-22-saeurechlorid 
• 6557-03-5 3β-methoxy-22,23-dinor-5-cholenic acid 
• 15019-28-0 (R)-1-bromo-2,3-dimethyl-butane 

Downstream Products

• 156767-69-0 (24S)-3β-hydroxyergost-5-en-6-one 
• 71486-03-8 ergost-5-en-7-on-3β-ol acetate 
• 6424-44-8 O-Benzoyl-haliclonastanol 
• 4356-09-6 (10S)-3c-Acetoxy-10r.13c-dimethyl-17c-((1S:4R)-1.4.5-trimethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren 
• 474-59-9 (10S)-3c-Hydroxy-10r.13c-dimethyl-17c-((1S:4R)-1.4.5-trimethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren 

Relevant articles and documents

Oxidized derivatives of dihydrobrassicasterol: Cytotoxic and apoptotic potential in U937 and HepG2 cells

The ability of phytosterol compounds to reduce plasma serum cholesterol levels in humans is well investigated. However, phytosterols are structurally similar to cholesterol with a double bond at the C5-6 position and are therefore susceptible to oxidation. Much research has been carried out on the biological effects of cholesterol oxidation products (COPs) in vitro. In contrast, there is less known about phytosterol oxidation products (POPs). From previous studies, it is apparent that oxidized derivatives of the phytosterols, β-sitosterol and stigmasterol, are cytotoxic in vitro but are less potent than their COP counterparts. In the present study, the cytotoxic and apoptotic potential of oxidized derivatives of dihydrobrassicasterol (DHB) including 5α,6α-epoxyergostan-3β-ol (α-epoxide), 5β,6β-epoxyergostan-3β-ol (β-epoxide), ergost-5-en-7-on- 3β-ol (7-keto), ergost-5-ene-3β,7β-diol (7-β-OH), and ergostane-3β,5α,6β-triol (triol) were evaluated in the U937 and HepG2 cell lines. In general, 7-keto, 7-β-OH, and triol derivatives had a significant cytotoxic impact on U937 and HepG2 cells. The oxides appear to be more toxic toward U937 cells. In line with previous findings, the POPs investigated in this study were less potent than the equivalent COPs. The results add to the body of data on the toxicity of individual POPs.

Marine sterols. X. Minor constituents of the sterols of the soft coral Sarcophyton glaucum

-