4682-78-4

Usage

Uses

Used in Agricultural Industry:
2,4-DICHLORO-6-PHENOXY-1,3,5-TRIAZINE is used as a herbicide for controlling broadleaf weeds in crops such as corn, wheat, and soybeans. It is effective in inhibiting the photosynthesis process in targeted plants, leading to their eventual death, thus ensuring the healthy growth of the desired crops and increasing agricultural productivity.

InChI:InChI=1/C9H5Cl2N3O/c10-7-12-8(11)14-9(13-7)15-6-4-2-1-3-5-6/h1-5H

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 108-95-2 phenol 
• 34888-05-6 (trichloromethoxy)benzene 
• 506-77-4 cyanogen chloride 

Downstream Products

• 36323-71-4 2-chloro-4-dimethylamino-6-phenoxy-1,3,5-triazine 
• 2972-65-8 2,4-diphenoxy-6-chloro-s-triazine 

Relevant academic research and scientific papers

1,3,5-Triazine as core for the preparation of dendrons

A unique property of 2,4,6-trichloro-1,3,5-triazine (TCT) is its ability to undergoes a nucleophilic aromatic substitution reaction (SNAr) under temperature-controlled conditions. Using a convenient and biologically friendly protocol, mono-substituted s-t

Phenol as a modulator in the chemical reactivity of 2,4,6-Trichloro-1,3,5-triazine: Rules of the Game II

2,4,6-Trichloro-1,3,5-triazine (TCT) is a privileged core that has the capacity to undergo sequential nucleophilic substitution reactions. Three nucleophiles, namely phenol, thiol and amine, were studied and the preferential order of incorporation on TCT

Novel Triazine Derivatives and Thermo-curable or Photosensitive Composition Comprising the Same

A compound represented by any one of Formulas A to [Chemical Formula C] and a photosensitive composition or a thermosetting composition including the same are disclosed. [Chemical Formula A] to [Chemical Formula C] The structure of a compound represented

Comparative study of multi-functional luminogens with 1,3,5-triazine as the core and phenothiazine or phenoxy donors as the peripheral moieties for non-doped/doped fluorescent and red phosphorescent OLEDs

A series of three-armed fluorescent emitters based on a 1,3,5-triazine acceptor as the central core and phenothiazine or phenoxy moieties as the different peripheral units, are designed and synthesized. All of them exhibit aggregation-induced emission enhancement and thermally activated delayed fluorescence. Photoluminescence quantum yields exceeded 37 and 67% for non-doped and doped solid-state samples respectively. The compounds were found to be capable of transporting both holes and electrons. The highest mobility values of more than 1 × 10?4 cm2V?1s?1 were obtained for the compound having three phenothiazine moieties at electric field of more than 1 × 106 Vcm?1. Additionally, three types of organic light emitting diodes based on these materials were fabricated. The device containing non-doped emission layer with the compound containing single phenothiazine moiety as the emitter gave maximum external quantum efficiency of 5.4%. The device with doped emission layer containing 5% solid solution of the compound having three phenothiazine moieties in an appropriate host gave maximum external quantum efficiency of 9.9%. The phosphorescent device hosted by the compound with single phenothiazine unit exhibited maximum external quantum efficiency of 10.3% and a low-efficiency roll-offs of 1% at 1000 cd/m2.

Metal-Assisted and Solvent-Mediated Synthesis of Two-Dimensional Triazine Structures on Gram Scale

Covalent triazine frameworks are an emerging material class that have shown promising performance for a range of applications. In this work, we report on a metal-assisted and solvent-mediated reaction between calcium carbide and cyanuric chloride, as cheap and commercially available precursors, to synthesize two-dimensional triazine structures (2DTSs). The reaction between the solvent, dimethylformamide, and cyanuric chloride was promoted by calcium carbide and resulted in dimethylamino-s-triazine intermediates, which in turn undergo nucleophilic substitutions. This reaction was directed into two dimensions by calcium ions derived from calcium carbide and induced the formation of 2DTSs. The role of calcium ions to direct the two-dimensionality of the final structure was simulated using DFT and further proven by synthesizing molecular intermediates. The water content of the reaction medium was found to be a crucial factor that affected the structure of the products dramatically. While 2DTSs were obtained under anhydrous conditions, a mixture of graphitic material/2DTSs or only graphitic material (GM) was obtained in aqueous solutions. Due to the straightforward and gram-scale synthesis of 2DTSs, as well as their photothermal and photodynamic properties, they are promising materials for a wide range of future applications, including bacteria and virus incapacitation.

Triazine natural gas drag reducer as well as synthesis method and application thereof

The invention discloses a triazine natural gas drag reducer. The molecular structural formula of the drag reducer is shown in the description. A synthesis method of the drag reducer comprises the following steps: dissolving cyanuric chloride in a solvent, dropwise adding an alcohol and an inorganic alkali at -15-0 DEG C, carrying out a reaction at -15-0 DEG C for 2-6 h, adding morpholine and the inorganic alkali after the reaction ends, carrying out a reaction at 50-100 DEG C for 6-12 h, washing the obtained reaction product with water after the reaction ends, and drying the washed reaction product to obtain the product. The drag reducer has a multi-polar end and a non-polar end, and has a good adsorption performance and excellent drag reducing and transportation increasing effects. The synthesis method has the advantages of simplicity, mild conditions, short time, low device requirements, and easiness in realization of large-scale industrial production.

Exploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups

In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4,6-Trichloro-1,3,5-triazine (TCT) is a tridentate linker that can accommodate three distinct nucleophiles. Herein, the reaction of azido triazine derivativ

Investigating Triorthogonal Chemoselectivity. Effect of Azide Substitution on the Triazine Core

An example of triorthogonal chemoselectivity is reported here for the first time. In this regard, a series of 43 reactions were performed using tridentate s-triazine as a model. In all of the possible cases, the three substitutions were carried out using

Design, Synthesis and Biological Evaluation of Novel Nonsteroidal Progesterone Receptor Antagonists Based on Phenylamino-1,3,5-triazine Scaffold

We report here the development of phenylamino-1,3,5-triazine derivatives as novel nonsteroidal progesterone receptor (PR) antagonists. PR plays key roles in various physiological systems, including the female reproductive system, and PR antagonists are promising candidates for clinical treatment of multiple diseases. By using the phenylamino-1,3,5-triazine scaffold as a template structure, we designed and synthesized a series of 4-cyanophenylamino-1,3,5-triazine derivatives. The synthesized compounds exhibited PR antagonistic activity, and among them, compound 12n was the most potent (IC50=0.30μM); it also showed significant binding affinity to the PR ligand-binding domain. Docking simulation supported the design rationale of the compounds. Our results suggest that the phenylamino-1,3,5-triazine scaffold is a versatile template for development of nonsteroidal PR antagonists and that the developed compounds are promising lead compounds for further structural development of nonsteroidal PR antagonists.

One-pot synthesis of triazines as potential agents affecting cell differentiation

Abstract: This paper outlines the synthesis of a number of structural analogs of 3-[(4,6-diphenoxy-1,3,5-triazin-2-yl)amino]benzoic acid which represent compounds with potential cardiogenetic activity. A one-pot protocol was developed for swift functionalization of the 1,3,5-triazine core without the need of isolating intermediates. The developed route starts from readily available 2,4,6-trichloro-1,3,5-triazine, displacing the chlorine atoms sequentially by aryloxy, arylamino, or arylthio moieties to enable access to molecules with three different substituents of this type in good yields. To facilitate purification, tert-butyl, methyl, and ethyl ester derivatives of the target compounds were initially synthesized. The tert-butyl esters could be readily hydrolyzed to the desired compounds, while reduction of the methyl and ethyl esters gave the corresponding benzylic alcohols in high yields, thereby expanding the substrate scope for future relevant cell assays. Graphical abstract: [Figure not available: see fulltext.].