468738-71-8

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 
• 95514-04-8 (R)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 92817-88-4 (2S)-3-{[tert-butyl(diphenyl)silyl]oxy}-2-methylpropanal 
• 106357-24-8 (3S,4S,5S)-6-(tert-butyldiphenylsiloxy)-4-hydroxy-3,5-dimethylhexan-1-ene 
• 814-68-6 acryloyl chloride 

Downstream Products

• 468738-78-5 (5S,6S)-6-{(1S)-2-[(tert-butyldiphenylsilyl)oxy]-1-methylethyl}-3,3,5-trimethyltetrahydro-2H-pyran-2-one 
• 237735-80-7 (5S,6S)-6-{(1S)-2-[(tert-butyldiphenylsilyl)oxy]-1-methylethyl}-5-methyltetrahydro-2H-pyran-2-one 
• 600715-00-2 (Z)-(2R,3S,4S,5S,7S,10S,11S,12S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-7,13-bis-(tert-butyl-diphenyl-silanyloxy)-11-methoxymethoxy-2,4,10,12-tetramethyl-tridec-8-enoic acid methyl ester 
• 600714-98-5 C₆₄H₁₀₂O₆Si₄ 
• 600714-95-2 (Z)-(3S,4S,5R,6S,8S,11S,12S,13S)-6-(tert-Butyl-dimethyl-silanyloxy)-8,14-bis-(tert-butyl-diphenyl-silanyloxy)-12-methoxymethoxy-3,5,11,13-tetramethyl-tetradeca-1,9-dien-4-ol 
• 600714-96-3 (Z)-(3S,4R,5R,6S,8S,11S,12S,13S)-6-(tert-Butyl-dimethyl-silanyloxy)-8,14-bis-(tert-butyl-diphenyl-silanyloxy)-12-methoxymethoxy-3,5,11,13-tetramethyl-tetradeca-1,9-dien-4-ol 
• 600714-94-1 C₅₅H₈₂O₅Si₃ 
• 1026877-90-6 (Z)-(2S,3S,5S,8S,9S,10S)-3-(tert-Butyl-dimethyl-silanyloxy)-5,11-bis-(tert-butyl-diphenyl-silanyloxy)-9-methoxymethoxy-2,8,10-trimethyl-undec-6-enal 
• 600714-93-0 (Z)-(3R,4S,6S,9S,10S,11S)-6,12-Bis-(tert-butyl-diphenyl-silanyloxy)-10-methoxymethoxy-3,9,11-trimethyl-dodeca-1,7-dien-4-ol 
• 600714-91-8 C₄₆H₆₂O₄Si₂ 
• 600714-92-9 (Z)-(3S,6S,7S,8S)-3,9-Bis-(tert-butyl-diphenyl-silanyloxy)-7-methoxymethoxy-6,8-dimethyl-non-4-enal 
• 600714-87-2 2,2-Dimethyl-propionic acid (Z)-(4S,5S,6S)-7-(tert-butyl-diphenyl-silanyloxy)-5-methoxymethoxy-4,6-dimethyl-hept-2-enyl ester 
• 600714-90-7 (Z)-(4S,7S,8S,9S)-10-(tert-Butyl-diphenyl-silanyloxy)-8-methoxymethoxy-7,9-dimethyl-deca-1,5-dien-4-ol 

Relevant academic research and scientific papers

Stereoselective synthesis of the C1-C13 fragment of (+)-discodermolide using asymmetric allyltitanations

(Matrix presented) The synthesis of the C1-C13 fragment of (+)-discodermolide has been achieved. The configurations of the stereogenic centers have been controlled by enantioselective allyl- and crotyltitanations of aldehydes, and the Z configuration of t

Formal total synthesis of (+)-methynolide

A formal total synthesis of (+)-methynolide was achieved in 23 steps highlighted by a crotylboration, a ring-closing metathesis, a Sharpless kinetic resolution of an allylic alcohol and a Takai reaction.

A short synthesis of the C1-C7 fragment of methymycin by ring-closing olefin metathesis

The synthesis of the C1-C7 fragment of methymycin was achieved via a ring-closing olefin metathesis employing Grubb's catalyst in the presence of Ti(OiPr)4.