4693-92-9

Upstream product

• 108-91-8 cyclohexylamine 
• 7782-50-5 chlorine 
• 101-83-7 N-cyclohexyl-cyclohexanamine 
• 108-98-5 thiophenol 
• 162466-77-5 N-allyl-N-cyclohexylcyclohexanamine 
• 1172120-23-8 C₂₀H₃₁NO 
• 122-60-1 Phenyl glycidyl ether 
• 1257857-54-7 C₆H₇O₃P*C₁₂H₂₃N 
• 1066-45-1 trimethyltin(IV)chloride 
• 108-94-1 cyclohexanone 
• 110-83-8 cyclohexene 

Downstream Products

• 100384-50-7 N-nitrodicyclohexylamine 
• 130574-96-8 (Zn(SC₆H₅)4)^(2-)*2((C₆H₁₁)2NH₂)⁽¹⁺⁾ 
• 131765-96-3 dicyclohexylamine borane complex 
• 101-83-7 N-cyclohexyl-cyclohexanamine 
• 1035-52-5 N,N-dicyclohexylbenzamide 
• 22824-16-4 dicyclohexyl-chloroamine 
• 947-92-2 N-nitrosodicyclohexylamine 
• 749247-79-8 (cyclohexyl)2NH2[Ph2Sn(Cl)(μ2-mercaptoacetate)] 

Relevant academic research and scientific papers

Mechanistic Investigation and Optimization of Photoredox Anti-Markovnikov Hydroamination

The reaction mechanism and the origin of the selectivity for the photocatalytic intermolecular anti-Markovnikov hydroamination of unactivated alkenes with primary amines to furnish secondary amines have been revealed by time-resolved laser kinetics measur

One-Pot Synthesis of Symmetrical Tertiary and Secondary Amines from Carbonyl Compounds, Ammonium Carbonate and Carbon Monoxide as a Reductant

Rh-catalyzed one-step synthesis of tertiary and secondary amines from aldehydes and ketones, ammonium carbonate serving as nitrogen source, and carbon monoxide as a reducing agent has been developed. Aliphatic and aromatic aldehydes lead to the corresponding tertiary symmetrical amines in 69–83 % yields. Aromatic and aliphatic ketones lead to the corresponding secondary symmetrical amines which were obtained in 62–79 % yields.

Delineating the critical role of acid additives in Mn-catalysed C-H bond functionalisation processes

Addition of co-catalytic Cy2NH to Mn-catalysed C-H bond activation reactions suggests that the conjugate acid, Cy2NH2X, influences catalysis. Here, acids are shown to positively influence C-H bond alkenylation catalysis in

Synthesis, spectroscopic characterization and crystal and molecular structures of phenylphosphonato SnR3 (R=Ph, Me) derivatives

Four new phenylphosphonato SnR3 (R=Ph, Me) derivatives have been synthesized and characterized by infrared and Moessbauer spectroscopy. The structure of catena-poly[PhPO3HSnMe3]n has been determined by single-crystal X-ray diffraction analysis. The SnIV atoms are five-coordinated in all compounds, with the SnC3O 2 framework in a trans trigonal bipyramidal arrangement and the PhPO3H- anions being in axial positions. The molecular structure of [PhPO3HSnMe3]n is arranged as a one-dimensional coordination polymer in which planar SnMe3 groups are axially bridged by -O-P-O- linkages of the PhPO3H- ligand. Neighboring chains are linked via O-H...O hydrogen bond interactions, generating a layered structure. In the R2NH 2(PhPO3H)2SnR′3 (R=Cy, Bu; R′=Ph, Me), the SnPh3 or SnMe3 residue is axially coordinated by two monodentate PhPO3H-. The role of the dialkylammonium cation, R2NH2+, is crucial in the lattice building via a hydrogen bond network. These hydrogen bonds contribute to the crystal stability and compactness and result in a three-dimensional arrangement. The aqua complex PhPO3(SnPh 3)2·2H2O has a discrete structure and the anion PhPO32- behaves as a bidentate ligand.

Convenient synthesis of cyclic carbonates from CO2 and epoxides by simple secondary and primary ammonium iodides as metal-free catalysts under mild conditions and its application to synthesis of polymer bearing cyclic carbonate moiety

Hydroiodides of secondary and primary amines effectively catalyzed the reaction of carbon dioxide and epoxides under mild conditions such as ordinary pressure and ambient temperature, to obtain the corresponding five-membered cyclic carbonates in moderate to high yields. Detailed investigation showed that the catalytic activity was highly affected by the counter anions of the ammonium salts; the iodides catalyzed efficiently the carbonate-forming reactions, whereas the bromide and chloride counterparts exhibited almost no catalysis. We also revealed that two important factors on the amine moieties that affected the catalytic reactions. First, the catalytic activity increased with increasing bulkiness of the substituents on the ammonium nitrogen atoms. Second, the catalysis became more efficient as the parent amines become more basic. Dicyclohexylammonium iodide was the best catalyst among the ammonium salts investigated in this study. As an application of this reaction system, we synthesized homo- and copolymers bearing epoxide pendant groups as substrates, which were converted with high efficiency into the corresponding homo- and copolymers bearing cyclic carbonate pendant groups under 1 atm at 45 °C. All polymers were easily purified simply by precipitation in water, and were isolated in high yields (>95%). 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013. Copyright

Catalytic C - H amination with unactivated amines through copper(II) amides

En route to catalysis: Two equivalents of the three-coordinate copper(II) amide [(Cl2NN)Cu]-NHAd participate in stoichiometric C - H amination by a H-atom abstraction/radical capture sequence. This active species may be generated through a copper(II) tert-butoxide intermediate to allow for the unprecedented catalytic amination of sp3-C - H bonds with unactivated alkylamines. This method greatly expands the range of amines for catalytic C - H amination since most protocols require N-based electron-withdrawing groups.

Reductive amine deallyl- and debenzylation with alkali metal in Silica Gel (M-SG)

Alkali metals in silica gel (the M-SG materials) are effective reagents for reductive deallylation, debenzylation, debenzhydrylation, and detritylation of amines. As such, these reagents provide a convenient alternative to traditional metal ammonia solutions for this class of deprotections.

Highly chemoselective Pd-C catalytic hydrodechlorination leading to the highly efficient N-debenzylation of benzylamines

(Equation Presented) In the presence of 1,1,2-trichloroethane, a novel procedure for the Pd-C catalytic N-debenzylation of benzylamines was established. The method proceeded in a synergistic catalytic system and directly gave the products as crystal amine hydrochlorides in practically quantitative yields.

Inhibitors of isoprenyl transferase

Provided are novel peptidomimetic isoprenyl transferase inhibitors, methods for synthesizing such inhibitors, and methods for the use of such inhibitors for the treatment of tumors.