470448-69-2Relevant academic research and scientific papers
The application of vinylogous iminium salt derivatives to an efficient relay synthesis of the pyrrole containing alkaloids polycitone A and B
Gupton, John T.,Miller, Robert B.,Krumpe, Keith E.,Clough, Stuart C.,Banner, Edith J.,Kanters, Rene P.F.,Du, Karen X.,Keertikar, Kartik M.,Lauerman, Nicholas E.,Solano, John M.,Adams, Bret R.,Callahan, Daniel W.,Little, Barrett A.,Scharf, Austin B.,Sikorski, James A.
, p. 1845 - 1854 (2007/10/03)
A new and efficient relay synthesis of the marine natural products polycitone A and B is described. The new strategy relies on the formation of 2,4-disubstituted pyrroles from a vinamidinium salt followed by electrophilic substitution at the 5-position of
Total syntheses of the marine pyrrole alkaloids polycitone A and B
Kreipl, Andreas T.,Reid, Caroline,Steglich, Wolfgang
, p. 3287 - 3288 (2007/10/03)
equation presented Polycitone B (2) was obtained in four steps from pyrrole dicarboxylic acid 3, including Friedel-Crafts reaction of the corresponding acid chloride with anisole. The conversion of 2 into polycitone A (1) was achieved in two steps via Mit
