470470-63-4

Upstream product

• 147252-93-5 (3S)-3-(benzyloxy)-2,2-dimethyl-4-penten-1-ol 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 277317-84-7 (2R/S,3R)-3-(Benzyloxy)tetrahydro-4,4-dimethylfuran-2-ol 
• 599-04-2 (R)-Pantolacton 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-39-0 benzyl bromide 
• 20374-33-8 (R)-(+)-3-(Benzyloxy)-4,5-dihydro-4,4-dimethyl-furan-2(3H)-on 
• 470470-82-7 ((S)-3-benzyloxy-2,2-dimethyl-pent-4-enyloxy)-tert-butyl-dimethyl-silane 

Downstream Products

• 470470-64-5 (S)-3-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethyl-pentanal 
• 1262295-44-2 (5S,7S)-7-benzyloxy-9-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-8,8-dimethyl-nonan-3-one 
• 1262295-46-4 [(S)-3-benzyloxy-4-((4R,6R)-6-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-butoxy]-tert-butyl-dimethyl-silane 
• 1262295-47-5 (S)-3-benzyloxy-4-((4R,6R)-6-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-butan-1-ol 
• 1262295-48-6 (S)-3-benzyloxy-4-((4R,6R)-6-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-butyraldehyde 
• 1262295-41-9 (E)-(S)-5-benzyloxy-6-((4R,6R)-6-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-4,4-dimethyl-hex-2-enoic acid ethyl ester 
• 1262295-40-8 [(2S,4S,6R)-4-benzyloxy-6-((R)-2-hydroxy-butyl)-3,3-dimethyl-tetrahydro-pyran-2-yl]-acetic acid ethyl ester 
• 1262295-42-0 [(2S,4S,6R)-4-benzyloxy-6-((R)-2-hydroxy-butyl)-3,3-dimethyl-tetrahydro-pyran-2-yl]-acetic acid 
• 1262295-43-1 (1S,5R,7R,9S,11S,15R,17R,19S)-9,19-bis-benzyloxy-5,15-diethyl-10,10,20,20-tetramethyl-4,14,21,22-tetraoxa-tricyclo[15.3.1.1(7,11)]docosane-3,13-dione 
• 1262295-49-7 [(S)-3-benzyloxy-4-((4R,6S)-6-ethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-2,2-dimethyl-butoxy]-tert-butyl-dimethyl-silane 
• 1352746-66-7 (5S,7S)-1,7-dibenzyloxy-9-tert-(butyldimethylsilyloxy)-5-[(S)-2-acetoxy-2-phenylacetoxy]-8,8-dimethylnonan-3-one 
• 1352746-65-6 (5S,7S)-1,7-dibenzyloxy-9-tert-(butyldimethylsilyloxy)-5-[(R)-2-acetoxy-2-phenylacetoxy]-8,8-dimethylnonan-3-one 
• 470470-81-6 (2R,6S)-2-acetoxymethyl-4-methylene-6-[(4S,6R,8S)-6,8,10-triacetoxy-4-benzyloxy-3,3-dimethyl-2-oxodecyl]tetrahydropyran 
• 1352746-52-1 (3S,5R,7S,15R,10E)-7-benzyloxy-1,15,16-tris-(tert-butyldimethylsilyloxy)-3,5-dihydroxy-8,8-dimethyl-3,5-O-isopropylidene-13-((E)-trimethylsilylmethylidene)hexadec-10-en-9-one 

Relevant academic research and scientific papers

Synthesis of molluscicidal agent cyanolide a macrolactone from D-(-)-Pantolactone

An efficient synthesis of potent molluscicidal agent cyanolide A, a glycosidic 16-membered macrolide, starting from D-(-)-pantolactone is reported. Highly stereoselective aldol, oxa-Michael addition, and Yamaguchi macrolactonization are the key steps in the present synthesis.

Synthesis of the C(1)-C(16) fragment of bryostatins using an 'ene' reaction between an allylsilane and an alkynone

The zinc(II) iodide mediated 'ene' reaction between (4R)-4,5-bis-(tert- butyldimethylsilyloxy)-2-(trimethylsilylmethyl)pent-1-ene (43) and (5S,7R,9S)-5,11-dibenzyloxy-4,4-dimethyl-7,9-dihydroxy-7,9-O- isopropylideneundec-1-yn-3-one (53) gave the (E)-vinyl

A stereoselective synthesis of the C(1)-C(16) fragment of the bryostatins

A synthesis of the C(1)-C(16) fragment of the brysostatins has been developed. Key steps are the stereoselective copper(I) catalysed addition of allylmagnesium bromide to an alkynyl ester, a condensation of a βγ-unsaturated aldehyde with a ketophosphonate

Synthesis of the C(1)-C(16) fragment of bryostatins

A synthesis of the C(1)-C(16) fragment 43 of the bryostatins is reported which features a stereoselective equivalent of an 'ene' reaction between the allylsilane 35 and the alkynone 33 and the stereoselective conjugate addition-cyclisation of the dienyl k