470716-48-4

Upstream product

• 106-54-7 p-Chlorothiophenol 
• 697260-70-1 3-[(4-chlorophenyl)-sulfanyl]-3-(2,5-difluorophenyl)-2-methyl-1-propanol 
• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 470716-52-0 2-[[(4-chlorophenyl)thio]methyl]-1,4-difluorobenzene 
• 852312-95-9 3-(4-chloro-benzenesulfonyl)-3-(2,5-difluoro-phenyl)-2-methyl-propionic acid methyl ester 

Relevant academic research and scientific papers

Aryl sulfones: A new class of γ-secretase inhibitors

The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors for the potential treatment of Alzheimer's disease is described.

PHENYLSULFOXIDE AND PHENYLSULFONE DERIVATIVES

The invention relates to phenylsulfoxide and phenylsulfone derivatives and to a method for producing them. The invention also relates to their use in the production of medicaments for the treatment and/or prophylaxis of diseases, especially of Alzheimer disease.