47091-20-3

Upstream product

• 2566-30-5 N-Methyl-L-phenylalanine 
• 100-51-6 benzyl alcohol 
• 1010385-23-5 C₂₄H₂₅NO₂ 
• 501-53-1 benzyl chloroformate 
• 37553-65-4 Boc-N-Me-Phe-OH 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 63-91-2 L-phenylalanine 
• 137393-05-6 N-((1,1-Dimethylethoxy)carbonyl)-N-methyl-L-phenylalanine phenylmethyl ester 

Downstream Products

• 168070-03-9 N-((1,1-Dimethylethoxy)carbonyl)-L-Leu-O-L-Leu-N(Me)-L-Phe phenylmethyl ester 
• 128140-12-5 leualacin 
• 168070-04-0 H-L-Leu-O-L-Leu-N(Me)-L-Phe phenylmethyl ester 
• 168069-98-5 H-β-Ala-O-D-Leu-L-Leu-O-L-Leu-N(Me)-L-Phe-OH 
• 168070-06-2 H-β-Ala-O-D-Leu-L-Leu-O-L-Leu-N(Me)-L-Phe phenylmethyl ester 
• 168070-05-1 N-((1,1-Dimethylethoxy)carbonyl)-β-Ala-O-D-Leu-L-Leu-O-L-Leu-N(Me)-L-Phe phenylmethyl ester 

Relevant academic research and scientific papers

Selective C-N bond oxidation: demethylation of N-methyl group in N-arylmethyl-N-methyl-α-amino esters utilizing N-iodosuccinimide (NIS)

Demethylation of N-methyl group in N-methyl-N-arylmethyl-α-amino esters was accomplished by the oxidation of the amino group using the N-iodosuccinimide (NIS)/acetonitrile system followed by treatment with O-methylhydroxylamine hydrochloride. This combina

Rational design and synthesis of unsaturated 2,5-dioxopiperazine derivatives as potential protein tyrosine kinase inhibitors

The first general method for the synthesis of a library of trifunctionalized (Z)-3-alkylidene-2,5-piperazinediones as potential protein tyrosine kinase inhibitors from commercially available amino compounds, α- keto acids and aldehydes using a novel cyclization/cleavage strategy on solid support is described.

Total synthesis of the cyclic depsipeptide leualacin

The fungal metabolite leualacin (1), a potent calcium channel antagonist, was synthesized in 15 steps from commercially available amino acids in 25% overall yield using standard solution methods. The synthesis is general and thus would accommodate the incorporation of amino acid replacements as well as the inclusion of peptide mimics and isosteres.