472963-08-9

Upstream product

• 472963-07-8 isopropyl 3-hydroxycyclohex-1-ene-1-carboxylate 
• 122689-79-6 isopropyl 3-oxocyclohex-1-ene-1-carboxylate 
• 98-89-5 Cyclohexanecarboxylic acid 
• 30434-55-0 isopropyl cyclohex-1-ene-1-carboxylate 
• 29548-87-6 1-bromocyclohexanecarboxylic acid chloride 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 51368-58-2 isopropyl 1-bromocyclohexanecarboxylate 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of enantiopure isopropyl (3R)- and (3S)-3-hydroxycyclohex-1-ene-1-carboxylates and their reduction to isomers of isopropyl 3-hydroxy-cyclohexane-1-carboxylate

Reduction of an α,β-unsaturated cyclic ketone with Geotrichum candidum affords the corresponding (S)-allylic alcohol, while enantiospecific oxidation of the corresponding racemic alcohols leaves the (R)-enantiomer unchanged, giving access to both enantiomeric forms. Subsequent chemical reduction of the double bond of these homochiral allylic alcohol allows all isomers of the corresponding cyclohexanols to be obtained.