30434-55-0

Upstream product

• 636-82-8 cyclohexene-1-carboxylic acid 
• 67-63-0 isopropyl alcohol 
• 51368-58-2 isopropyl 1-bromocyclohexanecarboxylate 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 98-89-5 Cyclohexanecarboxylic acid 
• 29548-87-6 1-bromocyclohexanecarboxylic acid chloride 

Downstream Products

• 18631-68-0 3-methyl-2,3,4,5,6,7-hexahydro-inden-1-one 
• 122689-79-6 isopropyl 3-oxocyclohex-1-ene-1-carboxylate 
• 472963-07-8 isopropyl 3-hydroxycyclohex-1-ene-1-carboxylate 
• 99438-50-3 (1S,3S)-3-hydroxycyclohexane-1-carboxylic acid isopropyl ester 
• 472963-08-9 isopropyl (3R)-3-hydroxycyclohex-1-ene-1-carboxylate 

Relevant academic research and scientific papers

Iridium(I)-catalyzed vinylic C-H borylation of 1-cycloalkenecarboxylates with bis(pinacolato)diboron

Ir(i)-catalyzed C-H borylation of 1-cycloalkenecarboxylic derivatives with bis(pinacolato)diboron affords various alkenylboronates with functional groups in excellent yields. This reaction was also used in a one-pot borylation/Suzuki-Miyaura cross-coupling procedure.

Chemoenzymatic synthesis of enantiopure isopropyl (3R)- and (3S)-3-hydroxycyclohex-1-ene-1-carboxylates and their reduction to isomers of isopropyl 3-hydroxy-cyclohexane-1-carboxylate

Reduction of an α,β-unsaturated cyclic ketone with Geotrichum candidum affords the corresponding (S)-allylic alcohol, while enantiospecific oxidation of the corresponding racemic alcohols leaves the (R)-enantiomer unchanged, giving access to both enantiomeric forms. Subsequent chemical reduction of the double bond of these homochiral allylic alcohol allows all isomers of the corresponding cyclohexanols to be obtained.