472979-51-4

Upstream product

• 472979-84-3 3-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,2-dimethyl-pentanoic acid methyl ester 
• 472979-90-1 3-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,2-dimethyl-pentan-1-ol 
• 472979-36-5 (3S)-3-tert-butyldimethylsilyloxy-5-p-methoxybenzyloxy-2,2-dimethylpentanal 
• 472979-31-0 (S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,2-dimethylpentanoic acid methyl ester 
• 128461-65-4 3-(p-methoxybenzyloxy)propanal 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 472979-46-7 6-(tert-butyl-dimethyl-silanyloxy)-8-(4-methoxy-benzyloxy)-5,5-dimethyl-oct-2-en-4-ol 

Relevant academic research and scientific papers

Toward the total synthesis of disorazole A(1) and C(1): asymmetric synthesis of a masked southern segment.

[reaction: see text] A highly convergent asymmetric synthesis of the masked southern segment of the antimitotic agent disorazole A(1) involves a Sonogashira coupling between a C1'-C10' enyne and a suitably protected C11'-C19' vinyl iodide. The central E,Z,Z-triene moiety is masked as a more stable ynediene.