473259-27-7

Upstream product

• 110-53-2 1-Bromopentane 
• 68078-10-4 1-p-phenylpiperidine-2-carbonitrile 
• 68274-97-5 dec-5-yn-1-ol 
• 7677-24-9 trimethylsilyl cyanide 
• 1310563-98-4 C₁₆H₂₃N 

Downstream Products

• 532985-81-2 1-pentyl-1-phenylpiperidine 

Relevant academic research and scientific papers

Synthesis of α-CN and α-CF3 N-heterocycles through tandem nucleophilic additions

Using a readily available secondary aminoalkyne as starting material, a powerful strategy was discovered to prepare precursors of biologically important unnatural cyclic aminoacids and fluorinated N-heterocycles with important ring sizes (e.g., 5-7) in a

Synthesis of 1-Azaspiroundecane ring system via Thorpe-Ziegler annulation of 2-Cyano-2-(4-Cyano-Tethered) Arylpiperidines

An efficient stereocontrolled route to the spiro[5.5]undecan framework of the histrionicotoxin alkaloids, employing anodic cyanation and Thorpe-Ziegler cyclization as key steps, is described. In the process of gaining information concerning the hydrolysis of the cyanoenamine function in 8, an unexpected intramolecular Friedel-Crafts type reaction provided the aza-fluorene 10.