475488-34-7 Usage
General Description
The chemical "7-[Trans-3-(1-Azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine" is a complex organic compound with a molecular structure that includes cyclobutyl, pyrimidin, and amine groups. It has potential pharmaceutical applications due to its ability to interact with biological systems, and it may be used in the development of new medications. The compound's specific properties and potential uses would need to be further studied and characterized through research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 475488-34-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,4,8 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 475488-34:
(8*4)+(7*7)+(6*5)+(5*4)+(4*8)+(3*8)+(2*3)+(1*4)=197
197 % 10 = 7
So 475488-34-7 is a valid CAS Registry Number.
475488-34-7Relevant articles and documents
A concise synthesis of a novel insulin-like growth factor i receptor (IGF-IR) inhibitor
Slade, Joel,Bajwa, Joginder,Liu, Hui,Parker, David,Vivelo, James,Chen, Guang-Pei,Calienni, John,Villhauer, Edwin,Prasad, Kapa,Repic, Oljan,Blacklock, Thomas J.
, p. 825 - 835 (2012/12/30)
An efficient synthesis of a potent insulin-like growth factor I receptor (IGF-IR) inhibitor AEW541 (1) is described. The key step in the synthesis is the cis-selective reductive animation of cyclobutanone, which sets up the desired 1,3-stereochemistry of the cyclobutane ring. The amino group thus generated is used as a handle to build the pyrrolopyrimidine ring. The final step resulting in 1 is accomplished by alkylation of in situ generated mesylate with azetidine.
