475575-54-3

Basic information

• Product Name: 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester
• Synonyms: 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester
• CAS NO: 475575-54-3
• Molecular Weight: 653.843
• Mol File: 475575-54-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester(475575-54-3)
• EPA Substance Registry System: 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester(475575-54-3)

Safety Data

• Hazardous Substances Data: 475575-54-3(Hazardous Substances Data)

Upstream product

• 501000-00-6 2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 
• 500999-99-5 2-{[(4-methoxyphenyl)(diphenyl)methyl]sulfanyl}ethan-1-amine 
• 501000-02-8 2-(4-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 
• 501000-01-7 2-amino-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 
• 84793-07-7 Fmoc-Glu-OtBu 

Downstream Products

• 153999-73-6 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-(2-mercapto-ethylcarbamoyl)-butyric acid 

Relevant articles and documents

An efficient synthesis of the ribozyme-folate conjugate

γ-Cysteamine modified folic acid was synthesized by reductive alkylation of N2-iBu-6-formylpterin with suitably protected cysteaminyl-L-glutamyl-p-aminobenzoic acid, followed by deprotection. Following activation with 2,2′-dipyridyl disulfide, this synthon was conjugated to the 5′-end of 5′-thiol modified ribozyme to afford target ribozyme-folate conjugate in a good yield.