501000-01-7

Basic information

• Product Name: L-Glutamine, N-[2-[[(4-methoxyphenyl)diphenylmethyl]thio]ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 501000-01-7
• Molecular Formula: C31H38N2O4S
• Molecular Weight: 534.72
• Mol File: 501000-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamine, N-[2-[[(4-methoxyphenyl)diphenylmethyl]thio]ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamine, N-[2-[[(4-methoxyphenyl)diphenylmethyl]thio]ethyl]-, 1,1-dimethylethyl ester(501000-01-7)
• EPA Substance Registry System: L-Glutamine, N-[2-[[(4-methoxyphenyl)diphenylmethyl]thio]ethyl]-, 1,1-dimethylethyl ester(501000-01-7)

Safety Data

• Hazardous Substances Data: 501000-01-7(Hazardous Substances Data)

Upstream product

• 500999-99-5 2-{[(4-methoxyphenyl)(diphenyl)methyl]sulfanyl}ethan-1-amine 
• 84793-07-7 Fmoc-Glu-OtBu 
• 501000-00-6 2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 

Downstream Products

• 153999-73-6 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-(2-mercapto-ethylcarbamoyl)-butyric acid 
• 475575-54-3 2-(4-amino-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 
• 501000-02-8 2-(4-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-benzoylamino)-4-{2-[(4-methoxy-phenyl)-diphenyl-methylsulfanyl]-ethylcarbamoyl}-butyric acid tert-butyl ester 

Relevant articles and documents

An efficient synthesis of the ribozyme-folate conjugate

γ-Cysteamine modified folic acid was synthesized by reductive alkylation of N2-iBu-6-formylpterin with suitably protected cysteaminyl-L-glutamyl-p-aminobenzoic acid, followed by deprotection. Following activation with 2,2′-dipyridyl disulfide, this synthon was conjugated to the 5′-end of 5′-thiol modified ribozyme to afford target ribozyme-folate conjugate in a good yield.