476313-39-0

Basic information

• Product Name: 4-methoxylcarbonylmethoxy-3-nitro-benzaldehyde
• Synonyms: 4-methoxylcarbonylmethoxy-3-nitro-benzaldehyde
• CAS NO: 476313-39-0
• Molecular Weight: 239.185
• Mol File: 476313-39-0.mol

Chemical Properties

• CAS DataBase Reference: 4-methoxylcarbonylmethoxy-3-nitro-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxylcarbonylmethoxy-3-nitro-benzaldehyde(476313-39-0)
• EPA Substance Registry System: 4-methoxylcarbonylmethoxy-3-nitro-benzaldehyde(476313-39-0)

Safety Data

• Hazardous Substances Data: 476313-39-0(Hazardous Substances Data)

Upstream product

• 3011-34-5 4-hydroxy-3-nitrobenzaldehyde 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 308815-81-8 methyl 2-[4-(hydroxymethyl)-2-nitrophenoxy]acetate 
• 200195-15-9 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde 
• 1246082-28-9 6-((4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 1246081-99-1 6-((4-phenylpiperidin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 1246082-03-0 6-((benzylamino)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 1246082-01-8 6-((phenylamino)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 308815-83-0 [4-(tert-butyl-dimethyl-silanyloxymethyl)-2-nitro-phenoxy]-acetic acid 
• 476313-37-8 benzyl 2-O-benzoyl-4-O-benzyl-3-O-chloroacetyl-6-O-(t-butylcarbonyl-2-nitrophenoxy-acetyl)-β-D-glucopyranoside 
• 476313-24-3 benzyl 2-O-benzoylbenzyl-3-O-chloroacetyl-6-O-(tert-butylcarbonyl-2-nitrophenoxyl-acetyl)-β-D-glucopyranoside 
• 476313-26-5 4-methoxylcarbonylmethoxy-3-nitro-benzoic acid 
• 476313-41-4 tert-butyl (4-methoxylcarbonylmethoxy)-3-nitro-benzoate 
• 476313-40-3 4-methoxycarbonylmethoxy-3-nitro-benzoic acid 

Relevant articles and documents

Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose) polymerase inhibitors

Structure based drug design of a series of novel 1,4-benzoxazin-3-one derived PARP-1 inhibitors are described. The synthesis, enzymatic & cellular activities and pharmacodynamic effects are described. Optimized analogs demonstrated inhibition of poly-ADP-ribosylation in SW620 tumor bearing nude mice through 24 h following a single dose.

POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS

Compounds of the following formula are provided for use in inhibiting Poly (ADP-ribose) Polymerase (PARP): wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds,

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On-resin real-time monitoring by a combination of a color test of (p-nitrobenzyl)pyridine and Disperse Red was developed for oligosaccharide synthesis. Copyright

Novel nitro Wang type linker for polymer support oligosaccharide synthesis; polymer supported acceptor

A novel linker designed for polymer support oligosaccharide synthesis is described. The nitro group carrying Wang resin type linker was stable under Lewis acidic glycosylation conditions. Selective reduction of the nitro group under the homogenous conditions was accompanied by spontaneous cyclization to release the oligosaccharides from polymer.