476471-88-2Relevant academic research and scientific papers
Photoredox Neutral Decarboxylative Hydroxyalkylations of Heteroarenes with α-Keto Acids
Deng, Guo-Jun,Huang, Huawen,Ji, Xiaochen,Wu, Xinzhuang,Yang, Zhonglin
supporting information, (2022/03/14)
Photoredox neutral decarboxylative hydroxyalkylations of heteroarenes with α-keto acids under mild conditions are described. Stable and readily available α-keto acids were employed as hydroxyalkylating reagents with only CO2released as the byproduct. A range of aromatic and aliphatic α-keto acids were successfully converted into hydroxyalkylated products with various heteroarenes. This transformation proceeded through a decarboxylation/Minisci addition/SCS sequence, generating a variety of valuable hydroxyalkylated heteroarenes.
New 6-ethoxyquinolines as simple optoquine analogues
Jones, Raymond C. F.,Collighan, Russell J.,Crane, Joanna,Hodges, Nikolas J.,Ling, Matthew S.,Stroud, Joanne
, p. 3185 - 3191 (2007/10/03)
Reaction of 6-ethoxylepidine (6-ethoxy-4-methylquinoline) with strong base and electrophiles leads to new derivatives, as possible optoquine analogues.
