4767-54-8 Usage
Uses
Used in Organic Synthesis:
3-(propan-2-ylidene)-2-benzofuran-1(3H)-one is used as a building block in organic synthesis for its unique reactivity and structural properties, enabling the creation of a wide range of organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-(propan-2-ylidene)-2-benzofuran-1(3H)-one is utilized as a key component in research aimed at developing new drugs, capitalizing on its potential biological activities.
Used in Anti-inflammatory Applications:
3-(propan-2-ylidene)-2-benzofuran-1(3H)-one is studied for its anti-inflammatory properties, which could be harnessed in the development of treatments for various inflammatory conditions.
Used in Anti-cancer Applications:
3-(propan-2-ylidene)-2-benzofuran-1(3H)-one is also being investigated for its anti-cancer properties, with potential implications for the development of novel therapeutic agents in oncology.
Used as a Precursor in Organic Compound Synthesis:
3-(propan-2-ylidene)-2-benzofuran-1(3H)-one serves as a precursor in the synthesis of various organic compounds, highlighting its versatility and importance in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 4767-54-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,6 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4767-54:
(6*4)+(5*7)+(4*6)+(3*7)+(2*5)+(1*4)=118
118 % 10 = 8
So 4767-54-8 is a valid CAS Registry Number.
4767-54-8Relevant academic research and scientific papers
Modified Julia Olefination on Anhydrides: Extension and Limitations. Application to the Synthesis of Maculalactone B
Dussart, Nicolas,Trinh, Huu Vinh,Gueyrard, David
supporting information, p. 4790 - 4793 (2016/10/14)
The preparation of exo-enol esters from cyclic anhydrides is reported using a modified Julia olefination. The reaction is highly stereoselective. The Smiles rearrangement can be performed in a one-pot process, giving a straightforward access to exo-enol lactones. Furthermore, the reaction was extended to semistabilized sulfones, and this methodology was applied to the synthesis of maculalactone B.
Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with ketones: Synthesis of 3-ylidenephthalides and their conversion to 2,2-disubstituted indan-1,3-diones including spirocyclic compounds
Watanabe,Morimoto,Tomoda,Iwanaga
, p. 1083 - 1086 (2007/10/02)
The Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with various ketones was investigated under the conditions: lithium bis(trimethylsilyl)amide (LHMDS) or sodium hydride in tetrahydrofuran, and cesium carbonate in isopropyl alcohol. The sequential treatment of the 3-ylidenephthalides with diisobutylaluminium hydride (DIBAL-H) and pyridinium dichromate (PDC) afforded 2,2-disubstituted indan-1,3-dione derivatives in modest to high overall yields.
