4768-43-8

Basic information

• Product Name: tert-butyl (S)-2-hydroxy-2-phenylacetate
• CAS NO: 4768-43-8
• Molecular Weight: 208.257
• Mol File: 4768-43-8.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: tert-butyl (S)-2-hydroxy-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (S)-2-hydroxy-2-phenylacetate(4768-43-8)
• EPA Substance Registry System: tert-butyl (S)-2-hydroxy-2-phenylacetate(4768-43-8)

Safety Data

• Hazardous Substances Data: 4768-43-8(Hazardous Substances Data)

Upstream product

• 16537-09-0 t-butyl phenylacetate 
• 7332-98-1 tert-butyl phenylglyoxylate 
• 117356-18-0 β-hydroxy β-phenyl acetate de t-butyle 
• 611-73-4 Benzoylformic acid 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 25726-04-9 phenylglyoxylyl chloride 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 75-65-0 tert-butyl alcohol 
• 1074-12-0 phenylglyoxal hydrate 
• 7322-88-5 (S)-acetylmandelic acid 
• 17199-29-0 (S)-Mandelic acid 
• 98-86-2 acetophenone 
• 13994-41-7 tert-butoxycarbonylmethyl nitrate 
• 7633-32-1 tert-butyl glyoxylate 

Downstream Products

• 1194481-20-3 t-butyl N-(Phth)-(D)-aminoxymandelate 
• 117356-18-0 β-hydroxy β-phenyl acetate de t-butyle 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE

Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.

Enantio- and chemoselective Br?nsted-acid/Mg(nBu) 2 catalysed reduction of α-keto esters with catecholborane

The first enantio- and chemoselective Br?nsted-acid catalysed reduction of α-keto esters with catecholborane has been developed. The α-hydroxy esters were obtained under mild reaction conditions in virtually quantitative yields and excellent enantioselectivities. With slight modifications both enantiomers can be obtained without any loss of selectivity. This journal is the Partner Organisations 2014.

Asymmetric addition of arylboronic acids to glyoxylate catalyzed by a ruthenium/Me-BIPAM complex

The enantioselective synthesis of α-hydroxy esters by ruthenium-catalyzed 1,2-addition of arylboronic acids to tert-butyl glyoxylate is described. The use of RuCl2(PPh3)3 with (R,R)-Me-BIPAM gave optically active mandelic acids of up to 99% ee. Addition of a fluoride salt such as potassium fluoride (KF) or caesium fluoride (CsF) was effective for achieving high enantioselectivities. The Royal Society of Chemistry 2012.