116325-19-0 Usage
Uses
Used in Organic Synthesis:
1H-Indole, 3-nitro-1-(phenylsulfonyl)is utilized as a key intermediate in organic synthesis for the creation of various chemical compounds. Its unique structure, which includes both a nitro and phenylsulfonyl group, allows for a wide range of chemical reactions and transformations, making it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1H-Indole, 3-nitro-1-(phenylsulfonyl)is employed as a precursor in the development of new drugs and pharmaceutical intermediates. Its presence in the synthesis of indole-based compounds, which are known for their diverse range of biological activities, positions it as a valuable component in the discovery and design of innovative therapeutic agents.
Used in the Development of Biologically Active Molecules:
1H-Indole, 3-nitro-1-(phenylsulfonyl)is also used in the research and development of biologically active molecules. Its structural features and reactivity make it a promising candidate for the creation of molecules with potential applications in medicine, such as new drug candidates or agents with specific biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 116325-19-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,2 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 116325-19:
(8*1)+(7*1)+(6*6)+(5*3)+(4*2)+(3*5)+(2*1)+(1*9)=100
100 % 10 = 0
So 116325-19-0 is a valid CAS Registry Number.
116325-19-0Relevant academic research and scientific papers
Pelkey,Gribble
, p. 1117 - 1122 (1999)
Treatment of N-protected indoles 3 with acetyl nitrate generated in situ at low temperatures affords the corresponding 3-nitroindoles 2 in good to excellent yields. Deprotection of 1-acetyl-3-nitroindole (2h) with DBU gives 3-nitroindole (1). Reaction of
Convenient synthesis of masked aminoindoles by indium mediated one-pot reductive acylation of 3- and 2-nitroindoles
Roy, Sujata,Gribble, Gordon W.
, p. 51 - 56 (2007/10/03)
Unstable 3- and 2-aminoindoles arc generated in situ by indium mediated reduction of 3- and 2-nitroindoles and capped as the stable amides (or carbamate) in moderate to high yields under mild conditions in a one-pot procedure.
One-step syntheses of the pyrrolo[3,4-b]indole and pyrrolo[2,3-b]indole ring systems from 3-nitroindoles
Pelkey, Erin T.,Gribble, Gordon W.
, p. 1873 - 1874 (2007/10/03)
The reaction of 1-ethoxycarbonyl-3-nitroindole with ethyl isocyanoacetate in the presence of DBU gives ethyl 4-ethoxycarbonyl-2,4-dihydropyrrolo[3,4-b]indole-3-carboxylate, averting a novel rearrangement that we previously reported with 3-nitro-1-phenylsu
