477584-90-0

Basic information

• Product Name: Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate
• Synonyms: Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate;methyl 2-(benzyloxycarbonylamino)-2-(tetrahydropyran-4-ylidene)acetate
• CAS NO: 477584-90-0
• Molecular Formula: C₁₆H₁₉NO₅
• Molecular Weight: 305
• Mol File: 477584-90-0.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate(477584-90-0)
• EPA Substance Registry System: Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate(477584-90-0)

Safety Data

• Hazardous Substances Data: 477584-90-0(Hazardous Substances Data)

Upstream product

• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 621-84-1 O-benzyl carbamate 
• 127357-37-3 methyl 2-(benzyloxycarbonylamino)-2-methoxyacetate 
• 79002-45-2 N-benzyloxycarbonyl-glycine 
• 114684-69-4 methyl 2-(benzyloxycarbonylamino)-2-(diethyloxyphosphoryl)acetate 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 

Downstream Products

• 894789-28-7 (S)-N-Cbz-pyranyl glycine methyl ester 
• 1188366-14-4 methyl 2-((tert-butoxy)carbonyl)amino-2-(tetrahydro-2H-pyran-4-yl)acetate 
• 182287-49-6 2-((tert-butoxy)carbonyl)amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid 
• 889949-63-7 2-amino-2-(tetrahydro-2H-pyran-4-yl)ethanol 
• 1035279-38-9 C₃₃H₄₃N₅O₅ 
• 1035278-84-2 C₂₈H₃₅N₅O₃ 
• 1009120-03-9 (S)-methoxycarbonylamino(tetrahydropyran-4-yl)acetic acid 
• 368866-32-4 (S)-pyranylglycine methyl ester 
• 477585-43-6 methyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate 
• 871261-11-9 (R)-N-Cbz-pyranylglycine methyl ester 

Relevant articles and documents

Bcl-2 INHIBITORS

Disclosed herein is a compound of Formula (I) for inhibiting Bcl-2 and treating disease associated with undesirable bcl-2 activity (Bcl-2 related diseases), a method of using the compounds disclosed herein for treating dysregulated apoptotic diseases incl

AMIDE COMPOUND

The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. In the formula (I), each symbol is as defined in the specification.

SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS

The present invention relates to a series of substituted compounds having the general formula (I), including their ste reoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3. R4, R5, and R6 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (κ) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS.