4789-95-1Relevant academic research and scientific papers
Efficient and sustainable laccase-catalyzed iodination of: P -substituted phenols using KI as iodine source and aerial O2 as oxidant
Sdahl, Mark,Conrad, Jürgen,Braunberger, Christina,Beifuss, Uwe
, p. 19549 - 19559 (2019/07/05)
The laccase-catalyzed iodination of p-hydroxyarylcarbonyl- and p-hydroxyarylcarboxylic acid derivatives using KI as iodine source and aerial oxygen as the oxidant delivers the corresponding iodophenols in a highly efficient and sustainable manner with yields up to 93% on a preparative scale under mild reaction conditions.
Phenolic oxidation of o,o'-dihalogenated phenols
Takahashi, Masakatsu,Konishi, Hironori,Iida, Satoshi,Nakamura, Kensuke,Yamamura, Shosuke,Nishiyama, Shigeru
, p. 5295 - 5302 (2007/10/03)
A detailed inspection of phenolic oxidation products derived from the o,o'-dihalogenated cresol derivatives (1a - 1e) indicated that the bromo and chloro substituents promoted the oxidation leading to the corresponding diaryl ethers, whereas the iodo derivatives provided the diaryls. Selective reduction of 6d and its tyrosine derivative afforded the corresponding diaryl ethers carrying two chlorine atoms (14, 15). Interpretation of the selectivity of the phenolic oxidation was attempted by employing theoretical calculations.
