48140-35-8

Basic information

• Product Name: 2-(2-Nitrophenyl)-1,3-dioxolane
• Synonyms: 2-(2-Nitrophenyl)-1,3-dioxolane
• CAS NO: 48140-35-8
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.17206
• EINECS: -0
• Mol File: 48140-35-8.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 306.2°C at 760 mmHg
• Flash Point: 146.5°C
• Appearance: /
• Density: 1.329g/cm³
• Vapor Pressure: 0.00142mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 2-(2-Nitrophenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Nitrophenyl)-1,3-dioxolane(48140-35-8)
• EPA Substance Registry System: 2-(2-Nitrophenyl)-1,3-dioxolane(48140-35-8)

Safety Data

• Hazardous Substances Data: 48140-35-8(Hazardous Substances Data)

Usage

General Description

2-(2-nitrophenyl)-1,3-dioxolane is a chemical compound that consists of a 1,3-dioxolane ring with a nitrophenyl group attached to one of the carbon atoms. It is commonly used in organic synthesis and pharmaceutical research as a building block for more complex molecules. Additionally, it is known for its potential application in the development of new drugs and materials due to its unique structure and reactivity. However, it is important to handle and dispose of this compound with care, as it can be hazardous if not managed properly. Overall, 2-(2-nitrophenyl)-1,3-dioxolane is a valuable chemical with numerous potential uses in various fields of science and industry.

InChI:InChI=1/C9H9NO4/c11-10(12)8-4-2-1-3-7(8)9-13-5-6-14-9/h1-4,9H,5-6H2

Upstream product

• 107-21-1 ethylene glycol 
• 552-89-6 2-nitro-benzaldehyde 
• 20627-73-0 1-(dimethoxymethyl)-2-nitrobenzene 
• 100-52-7 benzaldehyde 
• 107-07-3 2-chloro-ethanol 
• 15435-71-9 sodium acetoacetonate 

Downstream Products

• 172756-75-1 (2-nitrophenyl)<2-<(trimethylsilyl)oxy>ethoxy>acetonitrile 
• 96206-45-0 2-<(2-nitrobenzyl)oxy>ethanol 
• 60769-23-5 2-hydroxyethyl 2-nitrobenzoate 
• 23828-92-4 ambroxol hydrochloride 
• 50910-55-9 3,5-dibromo-2-amino benzaldehyde 

Relevant articles and documents

Activated Self-Resolution and Error-Correction in Catalytic Reaction Networks**

Understanding the emergence of function in complex reaction networks is a primary goal of systems chemistry and origin-of-life studies. Especially challenging is to create systems that simultaneously exhibit several emergent functions that can be independently tuned. In this work, a multifunctional complex reaction network of nucleophilic small molecule catalysts for the Morita-Baylis-Hillman (MBH) reaction is demonstrated. The dynamic system exhibited triggered self-resolution, preferentially amplifying a specific catalyst/product set out of a many potential alternatives. By utilizing selective reversibility of the products of the reaction set, systemic thermodynamically driven error-correction could also be introduced. To achieve this, a dynamic covalent MBH reaction based on adducts with internal H-transfer capabilities was developed. By careful tuning of the substituents, rate accelerations of retro-MBH reactions of up to four orders of magnitude could be obtained. This study thus demonstrates how efficient self-sorting of catalytic systems can be achieved through an interplay of several complex emergent functionalities.

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

Chiroptical Asymmetric Reaction Screening via Multicomponent Self-Assembly

Self-assembly of a stereodynamic phosphine ligand, Pd(II), and a chiral amine, amino alcohol, or amino acid generates characteristic UV and CD signals that can be used for quantitative stereochemical analysis of the bound substrate. A robust mix-and-measure chiroptical sensing protocol has been developed and used to determine the absolute configuration, ee, and yield of an amine produced by Ir-catalyzed asymmetric hydrogenation of an iminium salt. The analysis requires only 1 mg of the crude reaction mixture and minimizes cost, labor, time, and waste.