4816-00-6Relevant academic research and scientific papers
Total synthesis of altenusin and alterlactone
Cudaj, Judith,Podlech, Joachim
supporting information; experimental part, p. 371 - 374 (2012/03/27)
The resorcylic lactone alterlactone, a mycotoxin produced by alternaria sp., was synthesized for the first time. The total synthesis was achieved in nine steps with 69% yield starting with acetal-protected phloroglucinic acid and 6-bromopiperonal, where t
A concise benzotriazolyl-mediated synthesis of 9-methoxycepharanone A
Rys, Véronique,Couture, Axel,Deniau, Eric,Lebrun, Stéphane,Grandclaudon, Pierre
, p. 665 - 671 (2007/10/03)
A concise synthesis of 9-methoxycepharanone A is described. The key step is the benzotriazolyl-assisted assemblage of an arylmethyleneisoindolinone ring system comprising the enol ether unit. Radical cyclization followed by deprotections and ultimate formation of the methylenedioxy group complete the total synthesis of the title compound. Graphical Abstract.
Studies on Mannich Reaction of 1-Benzyltetrahydroisoquinolines
Bhakuni, D. S.,Kumar, Praveen
, p. 417 - 421 (2007/10/02)
The effect of substituents in Mannich cyclisation reaction of 1-benzyltetrahydroisoquinolines has been studied.Both para- and ortho-cyclisation products are formed when hydroxyl groups are present in the benzene ring of the benzylic moiety whereas only pa
Synthesis of Ring-Alkylated Isoproterenol Derivatives
Reitz, Allen,Avery, Mitchell A.,Verlander, Michael S.,Goodman, Murray
, p. 4859 - 4863 (2007/10/02)
2-Propyl-, 5-propyl-, and 6-propylisoproterenols (2a, 2b, and 1d, respectively) have been synthesized as models for polymer drug conjugates.Key intermediates were the propenylbenzaldehydes 3a-c.The (isopropylamino)phenethanol side chain was constructed fr
