481681-02-1

Basic information

• Product Name: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID
• Synonyms: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID;4-FLUORO-3-(HYDROXYMETHYL)PHENYLBORONIC ACID;4-Fluoro-3-(hydroxymethyl)benzeneboronic acid 98%;4-Fluoro-3-(hydroxymethyl)benzeneboronicacid98%;[4-Fluoro-3-(hydroxymethyl)phenyl]boronic acid ,98%;[4-fluoro-3-(hydroxymethyl)phenyl]boronic acid(SALTDATA: FREE);4-Fluoro-3-(hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride);4-Fluoro-3-(hydroxymethyl)phenyl
• CAS NO: 481681-02-1
• Molecular Formula: C₇H₈BFO₃
• Molecular Weight: 169.95
• Product Categories: blocks;BoronicAcids
• Mol File: 481681-02-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 124-126
• Boiling Point: 365.782 °C at 760 mmHg
• Flash Point: 175.019 °C
• Appearance: /
• Density: 1.353 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Keep Cold
• PKA: 8.39±0.10(Predicted)
• CAS DataBase Reference: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(481681-02-1)
• EPA Substance Registry System: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(481681-02-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 481681-02-1(Hazardous Substances Data)

Usage

Uses

suzuki reaction

InChI:InChI=1/C7H8BFO3/c9-7-2-1-6(8(11)12)3-5(7)4-10/h1-3,10-12H,4H2

Upstream product

• 374538-01-9 (4-fluoro-3-formylphenyl)boronic acid 
• 99725-13-0 (5-bromo-2-fluorophenyl)methanol 
• 5419-55-6 Triisopropyl borate 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 1312603-66-9 [4-(3-allyloxymethyl-4-fluorophenyl)-pyrimidin-2-yl]-[3-allyloxymethyl-4-(2-pyrrolidin-1-yl-ethoxy)phenyl]amine 
• 1312603-28-3 4-(3-allyloxymethyl-4-fluoro-phenyl)-2-chloropyrimidine 
• 1312603-21-6 [5-(2-chloro-pyrimidin-4-yl)-2-fluorophenyl]methanol 
• 1093064-47-1 3-(4-fluoro-3-hydroxymethylphenyl)-5-nitro-1-trityl-1H-indazole 
• 1093064-48-2 3-(4-fluoro-3-(2-methoxyxymethyl)-phenyl)-5-nitro-1-trityl-1H-indazole 
• 1093064-49-3 3-[4-fluoro-3-(2-methoxymethyl)-phenyl]-1-trityl-1H-indazol-5-ylamine 

Relevant articles and documents

PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR

Disclosed are a pyrimidinyl group-containing tricyclic compound and applications thereof in preparing a cancer-treating medicament. Specifically disclosed are a compound as represented by formula (I), a pharmaceutically acceptable salt of same, or an isomer thereof.

PHOSPHONATE CONJUGATES AND USES THEREOF

Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.