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4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 481681-02-1 Structure
  • Basic information

    1. Product Name: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID
    2. Synonyms: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID;4-FLUORO-3-(HYDROXYMETHYL)PHENYLBORONIC ACID;4-Fluoro-3-(hydroxymethyl)benzeneboronic acid 98%;4-Fluoro-3-(hydroxymethyl)benzeneboronicacid98%;[4-Fluoro-3-(hydroxymethyl)phenyl]boronic acid ,98%;[4-fluoro-3-(hydroxymethyl)phenyl]boronic acid(SALTDATA: FREE);4-Fluoro-3-(hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride);4-Fluoro-3-(hydroxymethyl)phenyl
    3. CAS NO:481681-02-1
    4. Molecular Formula: C7H8BFO3
    5. Molecular Weight: 169.95
    6. EINECS: N/A
    7. Product Categories: blocks;BoronicAcids
    8. Mol File: 481681-02-1.mol
  • Chemical Properties

    1. Melting Point: 124-126
    2. Boiling Point: 365.782 °C at 760 mmHg
    3. Flash Point: 175.019 °C
    4. Appearance: /
    5. Density: 1.353 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.542
    8. Storage Temp.: Keep Cold
    9. Solubility: N/A
    10. PKA: 8.39±0.10(Predicted)
    11. CAS DataBase Reference: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(481681-02-1)
    13. EPA Substance Registry System: 4-FLUORO-3-(HYDROXYMETHYL)BENZENEBORONIC ACID(481681-02-1)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 481681-02-1(Hazardous Substances Data)

481681-02-1 Usage

Uses

suzuki reaction

Check Digit Verification of cas no

The CAS Registry Mumber 481681-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,1,6,8 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 481681-02:
(8*4)+(7*8)+(6*1)+(5*6)+(4*8)+(3*1)+(2*0)+(1*2)=161
161 % 10 = 1
So 481681-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H8BFO3/c9-7-2-1-6(8(11)12)3-5(7)4-10/h1-3,10-12H,4H2

481681-02-1 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (F1090)  4-Fluoro-3-(hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride)  

  • 481681-02-1

  • 200mg

  • 790.00CNY

  • Detail
  • TCI America

  • (F1090)  4-Fluoro-3-(hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride)  

  • 481681-02-1

  • 1g

  • 2,990.00CNY

  • Detail
  • Alfa Aesar

  • (H52487)  4-Fluoro-3-(hydroxymethyl)benzeneboronic acid, 98%   

  • 481681-02-1

  • 250mg

  • 1390.0CNY

  • Detail
  • Alfa Aesar

  • (H52487)  4-Fluoro-3-(hydroxymethyl)benzeneboronic acid, 98%   

  • 481681-02-1

  • 1g

  • 4445.0CNY

  • Detail

481681-02-1Relevant articles and documents

PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR

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Paragraph 0471-0473, (2021/12/18)

Disclosed are a pyrimidinyl group-containing tricyclic compound and applications thereof in preparing a cancer-treating medicament. Specifically disclosed are a compound as represented by formula (I), a pharmaceutically acceptable salt of same, or an isomer thereof.

Controlled release system based on mesoporous silica nanoparticles and preparation method thereof

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Paragraph 0153-0155, (2020/08/30)

The invention relates to a meso-porous silicon oxide nanoparticle-based controlled release system and a preparation method thereof, and concretely relates to a meso-porous silicon oxide-based nanoparticle for controlled release, a controlled release system containing the nanoparticle, and a preparation method and a kit of the nanoparticle. The nanoparticle contains a phenyl borate functionalized meso-porous silicon oxide nanoparticle and a surface functionalized nanoparticle hole plugging agent which can be combined with phenyl borate. When no substrate exists, a nanometer silicon oxide system in the invention can realize zero early release; and after the substrate is added, a meso-porous tunnel plugged by the nanoparticle is opened in order to realize controlled release of a content. The method has the advantages of simple material synthesis, adjustable composition, and realization of responses to different substrates and different concentrations.

PHOSPHONATE CONJUGATES AND USES THEREOF

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Paragraph 00159; 00168-00169, (2020/07/31)

Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.

8-(BIARYL) QUINOLINE PDE4 INHIBITORS

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Page 50, (2010/02/06)

8-(biaryl) quinolines wherein the bi-aryl group at the 8-position is in a meta relationship to the quinoline group, are PDE4 inhibitors useful in the treatment of asthma, chronic bronchitis, chronic obstructive pulmonary disease, eosinophilic granuloma, psoriasis and other benign or malignant proliferative skin diseases, endotoxic shock, laminitis in horses, colic in horses, septic shock, ulcerative colitis, Crohn's disease, reperfusion injury of the myocardium and brain, inflammatory arthritis, chronic glomerulonephritis, atopic dermatitis, urticaria, adult respiratory distress syndrome, chronic obstructive pulmonary disease in animals, diabetes insipidus, allergic rhinitis, allergic conjunctivitis, vernal conjunctivitis, arterial restenosis, ortherosclerosis, atherosclerosis, neurogenic inflammation, pain, cough, rheumatoid arthritis, ankylosing spondylitis, transplant rejection, graft versus host disease, hypersecretion of gastric acid, bacterial, fungal induced sepsis, viral induced sepsis, fungal induced septic shock, viral induced septic shock, inflammation-mediated chronic tissue degeneration, cytokine-mediated chronic tissue degeneration, osteoarthritis, cancer, cachexia, muscle wasting, depression, memory impairment, tumour growth, or cancerous invasion of normal tissues.In another aspect, the present invention is directed to a method of enhancing cognition in a healthy subject comprising administering a safe cognition enhancing amount of phosphodiesterase-4 inhibitor. In particular, this invention is directed to a method of enhancing memory, learning, retention, recall, awareness and judgement in health subjects comprising administering a safe and cognition enhancing amount of a phosphodiesterase-4 inhibitor.

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