99725-13-0

Basic information

• Product Name: 5-Bromo-2-fluorobenzylamine hydrochloride
• Synonyms: (5-BROMO-2-FLUOROPHENYL)METHANOL;5-BROMO-2-FLUOROBENZYL ALCOHOL;RARECHEM AL BD 0325;5-Bromo-2-fluorobenzylamine hydrochloride
• CAS NO: 99725-13-0
• Molecular Formula: C₇H₆BrFO
• Molecular Weight: 205.03
• Product Categories: Fluorine Compounds;Anilines, Amides & Amines;Benzhydrols, Benzyl & Special Alcohols;Bromine Compounds
• Mol File: 99725-13-0.mol
• Article Data: 16

Chemical Properties

• Melting Point: 221-226 °C(lit.)
• Boiling Point: 261.6 °C at 760 mmHg
• Flash Point: 112 °C
• Appearance: /
• Density: 1.658 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-Bromo-2-fluorobenzylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-fluorobenzylamine hydrochloride(99725-13-0)
• EPA Substance Registry System: 5-Bromo-2-fluorobenzylamine hydrochloride(99725-13-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 99725-13-0(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-fluorobenzylamine hydrochloride is a chemical compound with the molecular formula C7H7BrFN2?HCl. It is used as a building block in the synthesis of various pharmaceuticals and is also employed in the preparation of organic compounds. This chemical is a white to off-white solid that is soluble in water and polar organic solvents. It is known for its ability to undergo a variety of chemical reactions, making it a valuable intermediate in organic synthesis. It is important to handle this compound with care and follow all safety protocols when working with it in the laboratory.

Upstream product

• 146328-85-0 5-bromo-2-fluoro-benzoic acid 
• 67-56-1 methanol 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 
• 99725-12-9 4-bromo-2-(bromomethyl)-1-fluorobenzene 
• 51437-00-4 5-bromo-2-fluorotoluene 
• 99748-26-2 2-(acetoxymethyl)-4-bromo-1-fluorobenzene 

Downstream Products

• 481681-02-1 (4-fluoro-3-(hydroxymethyl)phenyl)boronic acid 
• 530141-44-7 2-[(5-bromo-2-fluorophenyl)methyl]-2,3-dihydro-1H-isoindole-1,3-dione 
• 99725-14-1 4-bromo-1-fluoro-2-<<<(1,1-dimethylethyl)dimethylsilyl>oxy>methyl>benzene 

Relevant articles and documents

PHOSPHONATE CONJUGATES AND USES THEREOF

Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.

NRF2 REGULATORS

Provided are aryl analogs，pharmaceutical compositions containing them and their use as NRF2 regulators.

ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS

The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.