4819-22-1

Basic information

• Product Name: N-Acetyl-L-isoleucine ethyl ester
• Synonyms: N-Acetyl-L-isoleucine ethyl ester;(2S,3S)-Ethyl 2-acetaMido-3-Methylpentanoate
• CAS NO: 4819-22-1
• Molecular Formula: C₁₀H₁₉NO₃
• Molecular Weight: 201.26
• Mol File: 4819-22-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Acetyl-L-isoleucine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl-L-isoleucine ethyl ester(4819-22-1)
• EPA Substance Registry System: N-Acetyl-L-isoleucine ethyl ester(4819-22-1)

Safety Data

• Hazardous Substances Data: 4819-22-1(Hazardous Substances Data)

Usage

Uses

Used in Sports Nutrition Industry:
N-Acetyl-L-isoleucine ethyl ester is used as a supplement for its purported ability to enhance protein synthesis and reduce muscle fatigue, thereby improving muscle function and exercise performance. It is a popular ingredient in pre-workout supplements and muscle-building products, catering to the needs of athletes and fitness enthusiasts.
Used in Wellness Industry:
While primarily known for its muscle-supporting properties, N-Acetyl-L-isoleucine ethyl ester is also being explored for its potential cognitive function and brain health benefits. Although more research is required to confirm these effects, its presence in wellness products suggests a broader application in supporting overall health and well-being.

Upstream product

• 64-17-5 ethanol 
• 5854-47-7 (2S,3S)-N-acetyl-2-amino-3-methylpentanoic acid 
• 921-74-4 L-isoleucine ethyl ester 
• 75-36-5 acetyl chloride 
• 2256-90-8 ethyl N-acetyl-isoleucinate 

Downstream Products

• 3077-46-1 N-acetyl-L-isoleucine 
• 3077-46-1 N-acetyl-d-isoleucine 
• 2256-90-8 (R)-2-Acetylamino-3-methyl-pentanoic acid ethyl ester 

Relevant articles and documents

ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE

This application discloses a composition comprising a malodor compound and an anti-odor ingredient effective for reducing the presence or production of malodor. The composition may be topically applied to a subject and is useful for cosmetic conditions, pharmaceutical indications, or other objectives.

Competitive formation of 10- and 7-membered hydrogen-bonded rings of proline-containing model peptides

Intramolecularly hydrogen-bonded structures of proline-containing model peptides with a sequence of N-tert-butoxycarbonyl-prolyl-Xaa-NHCH3 [Xaa = Gly (glycyl), Ala (alanyl), Phe (phenylalanyl), Leu (leucyl), Ile (isoleucyl), and Val (valyl)] were studied by proton nuclear magnetic resonance and infrared spectroscopy. Variation of chemical shifts of amide protons with composition change of DMSO-d6/CDCl3 mixed solvents were found to be a good measure of intramolecular hydrogen bonding of peptides in CDCl3 solution. It has been shown that 10- and 7-membered hydrogen-bonded rings, which should have the β- and γ-turn like structures in proteins, respectively, form competitively with each other. It is suggested that the equilibrium between the two hydrogen-bonded rings is determined by steric hindrance due to a side chain of the Xaa residue. Free energies for formation of the 10- and 7-membered hydrogen-bonded rings, ΔG10 and ΔG7, were estimated from the solvent composition-dependent change of the chemical shifts. A good correlation between ΔG10 and the occurrence frequencies of residues Xaa at the (i + 2)th position for the β-turns in proteins has been found.

ENANTIOSELECTIVE HYDROLYSIS BY BAKER'S YEAST

Optically active N-acetylamino acid esters were obtained by enantioselective hydrolysis of their racemates using fermenting baker's yeast.