482655-65-2Relevant academic research and scientific papers
Improved synthesis and preparative scale resolution of racemic monastrol
Dondoni, Alessandro,Massi, Alessandro,Sabbatini, Simona
, p. 5913 - 5916 (2007/10/03)
The Yb(OTf)3 catalyzed Biginelli cyclocondensation reaction of 3-hydroxybenzaldehyde, ethyl acetoacetate and thiourea afforded the corresponding dihydropyrimidine-2-thione, called monastrol, in 95% isolated yield. The chiral resolution of racem
