4832-27-3Relevant academic research and scientific papers
Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy
Sintas, Jose A.,Macareno, Norberto J.,Vitale, Arturo A.
, p. 97 - 101 (2000)
The preparation and spectral properties (MS, IR and NMR) of 8-[10B]-dihydroxyborylharmine (III) are described. A general synthetic method was developed for an efficient production of boronated harmine; a potential agent for boron neutron capture therapy (BNCT) in brain.
Preparation of boric-10 acid applied in shielded materials of nuclear industry
Zhang, Lei,Zhang, Weijiang,Xu, Jiao
, p. 249 - 256 (2015/02/19)
Because of the superior features of boron-10 isotope in absorbing hot neutrons, boric-10 acid (H310BO3) has been used widely in nuclear industry, like as additive in primary loop of pressurized water reactor and as control rod and other shielded materials in nuclear reactor. Boric-10 acid is obtained from boron-10 trifluoride (10BF3) by esterification and hydrolyzation. In this study, the preparation of trimethyl borate-10 [(CH3O)3B] from boron-10 trifluoride (10BF3) obtained through chemical exchange rectification was investigated. The kinetics of esterification reaction was controlled by second order pseudo homogeneous reaction. The activation energy was 685.5 KJ/mol. In addition, the hydrolyzation of trimethyl borate-10 was investigated as a function of pH, temperature and molar ratio of water to trimethyl borate-10. Under optimum process conditions, higher yield of boric-10 acid with nuclear industrial purity grade was realized.
