488098-44-8

Basic information

• Product Name: α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanamine
• Synonyms: α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanamine
• CAS NO: 488098-44-8
• Molecular Weight: 271.205
• Mol File: 488098-44-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanamine(488098-44-8)
• EPA Substance Registry System: α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanamine(488098-44-8)

Safety Data

• Hazardous Substances Data: 488098-44-8(Hazardous Substances Data)

Upstream product

• 289686-70-0 α,α-Dimethyl-3,5-bis(trifluoromethyl)benzeneacetic Acid 
• 334477-48-4 methyl 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoate 

Downstream Products

• 645378-55-8 1,1-dimethylethyl-4-[3-({1-[3,5-bis(trifluoromethyl)phenyl]-1-methylethyl}amino)-1-(4-fluorophenyl)-3-oxopropyl]-1-piperidinecarboxylate 

Relevant articles and documents

4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I.

A series of novel 4,4-disubstituted cyclohexylamine based NK(1) antagonists is described. The effect of changes to the C(1)-C(4) relative stereochemistry on the cyclohexane ring and replacements for the flexible linker are discussed, leading to the identification of compounds with high affinity and good in vivo duration of action.