4885-93-2Relevant articles and documents
Synthesis of the first novel pyrazole thioglycosides as deaza ribavirin analogues
Abu-Zaied, Mamdouh A.,Elgemeie, Galal H.
, p. 713 - 725 (2017)
This study reports a novel and efficient method for the synthesis of the first reported novel class of thiopyrazoles and their corresponding thioglycosides. These series of compounds were designed through the reaction of hydrazine derivatives with sodium dithiolate salt 2 in EtOH at ambient temperature to give the corresponding sodium 5-amino-4-cyano-1H-pyrazole-3-thiolates 4a-d. The latter compounds were treated with α-acetobromoglucose 6a and α-acetobromogalactose 6b in DMF at ambient temperature to give in an excellent yields the corresponding pyrazole S-glycosides 7a-h. Ammonolysis of the pyrazole thioglycosides 7a-h afforded the corresponding free thioglycosides 8a-h.
Synthesis of some 2-ylidene-1,3-dithiolanes
Lipin,Ershov,Belikov, M. Yu.,Fedoseev
, p. 147 - 149 (2017)
Convenient procedures have been developed for the synthesis of 2-(1,3-dithiolan-2-ylidene)- malononitriles and 2-cyano-2-(1,3-dithiolan-2-ylidene)acetamides from disodium alk-1-ene-1,1-dithiolates and 1,2-dichloroalkanes, as well as from malononitrile or cyanoacetamide in a one-pot mode.
Synthesis and antimicrobial evaluation of novel N-substituted 4-ethylsulfanyl-2-pyridones and triazolopyridines
Azzam, Rasha A.,Elgemeie, Galal H.
, p. 62 - 70 (2018/12/04)
The design and development of new methods for the synthesis of antimicrobial drugs is an important goal currently for medicinal chemistry. Sixteen novel N-substituted-amino-, N-arylsulfonylamino-, and N-aryl-4-ethylsulfanyl-2-pyridones were synthesized. A
Sulfur-rich binaphthyl diimide derivative, and preparation method and application thereof
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Paragraph 0054; 0058; 0063, (2019/08/30)
The invention discloses a sulfur-rich binaphthyl diimide derivative, and a preparation method and application thereof, and belongs to the technical field of organic semiconductors. The sulfur-rich binaphthyl diimide derivative, namely the sulfur-containing naphthalene diimide derivative has a structure represented as the following formula (I), wherein R and R are cyano-containing groups, andR, R, R and R are separately selected from alkyl groups with 1-20 carbon atoms. According to the sulfur-containing naphthalene diimide derivative disclosed by the invention, heteroatom functional groups (S) are introduced in 2, 3, 6 and 7 sites of naphthalene rings, and cyano groups are introduced, so that spectrum absorption, the highest occupied molecular orbital (HOMO) value and the lowest unoccupied molecular orbital (LUMO) value of naphthalene diimide derivative molecules can be adjusted by the heteroatom functional groups, and then requirements of various functional materials can be met.