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2-amino-1,3,5-benzenetricarboxylic acid, also known as 2-aminoisophthalic acid, is an organic compound with the chemical formula C8H7NO6. It is a white crystalline solid that is soluble in water and slightly soluble in ethanol. 2-amino-1,3,5-benzenetricarboxylic acid is an isomer of 1,3,5-benzenetricarboxylic acid, with the key difference being the presence of an amino group (-NH2) at the 2-position. 2-amino-1,3,5-benzenetricarboxylic acid is an important intermediate in the synthesis of various pharmaceuticals, dyes, and other chemical products. It is also used as a chelating agent in analytical chemistry due to its ability to form stable complexes with metal ions. The compound can be synthesized through various methods, including the condensation of phthalic anhydride with ammonia or the hydrolysis of 2-nitro-1,3,5-benzenetricarboxylic acid.

489-96-3

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489-96-3 Usage

Structure

Benzene ring with three carboxylic acid groups and an amino group attached at different positions

Applications

Pharmaceuticals
Coordination chemistry
Building block in organic synthesis
Production of polymers
Precursor for the synthesis of various organic compounds

Medical Research

Investigated for potential treatment of certain medical conditions and diseases

Check Digit Verification of cas no

The CAS Registry Mumber 489-96-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 489-96:
(5*4)+(4*8)+(3*9)+(2*9)+(1*6)=103
103 % 10 = 3
So 489-96-3 is a valid CAS Registry Number.

489-96-3Downstream Products

489-96-3Relevant academic research and scientific papers

Functionalization of Metal-Organic Frameworks To Achieve Controllable Wettability

Rubin, Heather N.,Reynolds, Melissa M.

, p. 5266 - 5274 (2017)

The overall versatility of a material can be immensely expanded by the ability to controllably tune its hydrophobicity. Herein we took advantage of steric bias to demonstrate that tricarboxylate metal-organic frameworks (MOFs) can undergo covalent postsyn

Method for synthetizing 2-amino-1, 3, 5-benzenetricarboxylic acid and application thereof for preparation of NH2-MOF-808

-

Paragraph 0022; 0034; 0038; 0042; 0046; 0049; 0053; 0056, (2019/06/27)

The invention belongs to the field of preparation and application of organic compounds and metal-organic framework compounds, and discloses a method for synthetizing 2-amino-1, 3, 5-benzenetricarboxylic acid and an application thereof for preparation of a

Functionalized Eu(III)-based nanoscale metal-organic framework for enhanced targeted anticancer therapy

Chen, Pan,Huang, Ya-Fan,Xu, Guang-Yu,Xue, Jin-Ping,Chen, Juan-Juan

, p. 619 - 627 (2019/03/13)

To improve the cancer targeting and anticancer efficacy, the multifunctional Eu-based metal-organic framework (EuBTC) is post-synthetically modified with a targeting moiety folic acid and a zinc phthalocyanine photosensitizer. In addition, this nanosphere

Amino substituted Cu3(btc)2: A new metal-organic framework with a versatile functionality

Peikert, Katharina,Hoffmann, Frank,Fr?ba, Michael

supporting information, p. 11196 - 11198 (2013/01/15)

A new amino substituted tricarboxylate linker and the new metal-organic framework Cu3(NH2btc)2 have been synthesised. The new MOF shows good adsorption properties and is suitable for postsynthetic modification to form an a

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