16198-01-9

Basic information

• Product Name: (+)-Catechin-pentaacetate
• Synonyms: (+)-Catechin-pentaacetate;(2R)-2α-(3,4-Diacetoxyphenyl)-3β,5,7-triacetoxy-3,4-dihydro-2H-1-benzopyran;(2R)-3,4-Dihydro-2α-(3,4-dihydroxyphenyl)-2H-1-benzopyran-3β,5,7-triol pentaacetate;2α-[3,4-Bis(acetyloxy)phenyl]chroman-3β,5,7-triol 3,5,7-triacetate;3,4-Dihydro-2α-(3,4-diacetoxyphenyl)-3β,5,7-triacetoxy-2H-1-benzopyran;Catechol pentaacetate
• CAS NO: 16198-01-9
• Molecular Formula: C₂₅H₂₄O₁₁
• Molecular Weight: 500
• Mol File: 16198-01-9.mol
• Article Data: 28

Chemical Properties

• Melting Point: 130-132 °C
• Boiling Point: 624.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (+)-Catechin-pentaacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Catechin-pentaacetate(16198-01-9)
• EPA Substance Registry System: (+)-Catechin-pentaacetate(16198-01-9)

Safety Data

• Hazardous Substances Data: 16198-01-9(Hazardous Substances Data)

Usage

General Description

(+)-Catechin-pentaacetate is a chemical compound derived from catechin, a type of natural phenol and antioxidant found in various plants such as tea, grapes, and cocoa. It is formed by esterifying catechin with five acetyl groups, resulting in a more stable form of the compound. (+)-Catechin-pentaacetate has been studied for its potential health benefits, including its antioxidant and anti-inflammatory effects. It has also been investigated for its potential use in pharmaceutical and cosmetic products due to its ability to protect cells from oxidative damage and its anti-aging properties. Additionally, research has suggested that (+)-Catechin-pentaacetate may have potential applications in the development of new drugs for the treatment of various diseases.

Upstream product

• 67-56-1 methanol 
• 108-24-7 acetic anhydride 
• 65052-92-8 (+/-)-2,3-trans-3,4-trans-4-hydroxy-3,5,7,3',4'-pentaacetoxyflavan 
• 154-23-4 catechin 
• 6685-67-2 (+/-)-taxifolin pentaacetate 
• 154-23-4 (+/-)-epicatechin 
• 132400-73-8 (+/-)-catechin 3,7,3',4'-tetraacetate 
• 7295-85-4 catechin 
• 154-23-4 catechin 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 6685-67-2 2-(3,4-diacetoxyphenyl)-4-oxochroman-3,5,7-triyl triacetate 
• 127-09-3 sodium acetate 
• 490-46-0 (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 
• 28684-46-0 guibourtinidol-(4α<*>8)-catechin 

Downstream Products

• 116935-88-7 acetate of (+)-catechin 
• 528-58-5 cyanidin chloride 
• 51196-02-2 5,7,3',4'-tetra-O-methylepicatechin 
• 104263-86-7 ent-catechin 3',4',5,7-tetra-O-methyl ether 
• 19611-22-4 3',4',5,7-tetra-O-methylcatechin 
• 51126-02-4 4β-bromopenta-O-acetyl-(+)-catechin 
• 51126-02-4 4β-bromopenta-O-acetyl-(-)-epicatechin 
• 1438268-67-7 C₄₇H₁₈⁽²⁾H₂₈O₈ 
• 1309871-89-3 C₄₉H₂₀⁽²⁾H₂₈O₉ 
• 1438268-70-2 C₅₄H₂₂⁽²⁾H₂₈O₉ 
• 1438268-48-4 C₄₉H₁₉⁽²⁾H₂₈BrO₉ 
• 1438268-55-3 C₅₄H₂₁⁽²⁾H₂₈BrO₉ 
• 1438268-49-5 C₅₀H₈⁽²⁾H₃₅BrO₆ 
• 1438268-50-8 C₅₀H₈⁽²⁾H₃₅IO₆ 

Relevant articles and documents

Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 10: Identification of inhibitors for the liver microsomal acetoxycoumarin: Protein transacetylase

The quantitative structure-activity relationship (QSAR) studies conducted by us earlier revealed the cardinal role of the pyran ring carbonyl group in the acetoxy polyphenolic compounds for the acetoxy polyphenol:protein transacetylase (TAase) activity. H

Catechin Derivatives as Inhibitor of COVID-19 Main Protease (Mpro): Molecular Docking Studies Unveil an Opportunity Against CORONA

Background: A newly emergent strain of coronavirus (COVID-19) has affected almost the whole of the world’s population. Currently, there is no specific vaccine or drug against COVID-19. Xu et al. (2020) built a homolog model of SARS-CoV-2 Mpro b

Preparation method and application of hydroxyl cinnamyl ester type catechin

The invention relates to a preparation method and application of hydroxyl cinnamyl ester type catechins. The hydroxyl cinnamyl ester type catechins comprise four catechins which are respectively namedas epicatechin trans-coumarate, epicatechin trans-caffeic acid ester, epigallocatechin trans-coumarate and epigallocatechin trans-caffeic acid ester. The hydroxyl cinnamyl ester type catechins are prepared by the following steps: carrying out four steps of full acetylation on epicatechin and epigallocatechin, removal of acetyl on phenolic hydroxyl, silanizing of phenolic hydroxyl and removal of 3-acetyl, then respectively esterifying with acetylated caffeic acid or coumaric acid acyl chloride, and removing a protecting group. The preparation method of the four catechins is simple and mild inconditions, and can be completed under general experimental conditions. The four hydroxycinnamyl ester type catechins have a certain inhibition effect on the activity of alpha-glucosidase, can be usedfor hypoglycemic drugs, and have important significance in the fields of agriculture and medicine.