492-93-3Relevant articles and documents
Synthesis of a carbohydrate-centered C-glycoside cluster
Dubber, Michael,Lindhorst, Thisbe K.
, p. 755 - 760 (2001)
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Controlling Sugar Deoxygenation Products from Biomass by Choice of Fluoroarylborane Catalyst
Seo, Youngran,Lowe, Jared M.,Gagné, Michel R.
, p. 6648 - 6652 (2019/08/26)
The feedstocks from biomass are defined and limited by nature, but through the choice of catalyst, one may change the deoxygenation outcome. We report divergent but selective deoxygenation of sugars with triethylsilane (TESH) and two fluoroarylborane catalysts, B(C6F5)3 and B(3,5-CF3)2C6H3)3 (BAr3,5-CF3). To illustrate, persilylated 2-deoxyglucose shows exocyclic C-O bond cleavage/reduction with the less sterically congested BAr3,5-CF3, whereas endocyclic C-O bond cleavage/reduction predominates with the more Lewis acidic B(C6F5)3. Chiral furans and linear polyols can be selectively synthesized depending on the catalysts. Mechanistic studies demonstrate that the resting states of these catalysts are different.
Total Synthesis of Neodysiherbaine A via 1,3-Dipolar Cycloaddition of a Chiral Nitrone Template
Hirai, Toshihiro,Shibata, Kohki,Niwano, Yohei,Shiozaki, Masao,Hashimoto, Yoshimitsu,Morita, Nobuyoshi,Ban, Shintaro,Tamura, Osamu
supporting information, p. 6320 - 6323 (2017/12/08)
The total synthesis of neodysiherbaine A was achieved via 1,3-dipolar cycloaddition of a chiral nitrone template with a sugar-derived allyl alcohol in the presence of MgBr2·OEt2. This cycloaddition constructed the C2 and C4 asymmetric centers in a single step. Then reductive cleavage, intramolecular SN2 reaction of the tertiary alcohol, and oxidation of the primary alcohol afforded neodysiherbaine A.
Intramolecular dehydration of mannitol in high-temperature liquid water without acid catalysts
Yamaguchi, Aritomo,Sato, Osamu,Mimura, Naoki,Shirai, Masayuki
, p. 45575 - 45578 (2014/12/12)
Intramolecular dehydration of mannitol in high-temperature liquid water without adding any hazardous acid catalysts and its kinetic analyses were carried out. The dehydration behavior of mannitol was compared with that of sorbitol. 2,5-Anhydromannitol and 1,4-anhydromannitol were major products from the mannitol monomolecular dehydration in contrast with the only major product, 1,4-anhydrosorbitol, from the sorbitol monomolecular dehydration.