4940-52-7

Basic information

• Product Name: 2-Benzylidene-6-methoxybenzofuran-3(2H)-one
• Synonyms: 2-Benzylidene-6-methoxybenzofuran-3(2H)-one;2-Phenyl-methylene-6-methoxy-3(2H)-benzofuranone;6-Methoxyaurone
• CAS NO: 4940-52-7
• Molecular Formula: C₁₆H₁₂O₃
• Molecular Weight: 252.26
• Mol File: 4940-52-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 145-146 °C
• Boiling Point: 438.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.274±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Benzylidene-6-methoxybenzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzylidene-6-methoxybenzofuran-3(2H)-one(4940-52-7)
• EPA Substance Registry System: 2-Benzylidene-6-methoxybenzofuran-3(2H)-one(4940-52-7)

Safety Data

• Hazardous Substances Data: 4940-52-7(Hazardous Substances Data)

Upstream product

• 39273-61-5 (E)-1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 60965-24-4 2-bromo-1-(2-hydroxy-4-methoxy-phenyl)-ethanone 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 62536-69-0 2'-acetoxy-4'-methoxychalcone 
• 100-52-7 benzaldehyde 
• 133828-51-0 Acetic acid 2-(2-bromo-3-methoxy-3-phenyl-propionyl)-5-methoxy-phenyl ester 
• 49753-64-2 6-methoxy-benzofuran-2,3-dione 
• 16721-45-2 triphenyl(phenylmethylene)phosphorane 
• 15832-09-4 6-methoxy-3-coumaranone 

Downstream Products

• 2237-36-7 4-methoxysalicylic acid 
• 65-85-0 benzoic acid 
• 22141-31-7 4’-methoxy-2’-hydroxyl-dihydrochalcone 
• 108197-77-9 5-Methoxy-2-(7-methoxy-4-phenyl-benzo[4,5]furo[3,2-b]pyridin-2-yl)-phenol 
• 108197-64-4 4-Bromo-2-(7-methoxy-4-phenyl-benzo[4,5]furo[3,2-b]pyridin-2-yl)-6-methyl-phenol 
• 108197-59-7 7-Methoxy-2,4-diphenyl-benzo[4,5]furo[3,2-b]pyridine 

Relevant articles and documents

A Palladium-Catalyzed Oxa-(4+4)-Cycloaddition Strategy towards Oxazocine Scaffolds

A Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation.

The Wittig reaction of benzofuran-2,3-diones

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Synthesis of Pyridobenzofurans

Some diarylpyridobenzofurans have been conveniently synthesised in 50-65percent yield by the condensation of 2-arylidene-6-methoxycoumaran-3-ones (III) with phenacylpyridinium halides in the presence of ammonium acetate.In a similar manner some 5-h