494799-14-3

Basic information

• Product Name: methyl 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate
• Synonyms: 3-Cyclohexyl-2-phenylindole-6-carboxylic acid methyl ester; Methyl 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate
• CAS NO: 494799-14-3
• Molecular Formula: C₂₂H₂₃NO₂
• Molecular Weight: 333.4235
• Mol File: 494799-14-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 522.1°C at 760 mmHg
• Flash Point: 269.6°C
• Density: 1.164g/cm³
• Vapor Pressure: 5.34E-11mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: methyl 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate(494799-14-3)
• EPA Substance Registry System: methyl 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate(494799-14-3)

Safety Data

• Hazardous Substances Data: 494799-14-3(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 50820-65-0 indole-6-carboxylic acid methyl ester 
• 1670-82-2 Indole-6-carboxylic acid 
• 494799-16-5 3-(cyclohex-1-en-1-yl)-1H-indole-6-carboxylic acid 
• 494799-17-6 3-cyclohexyl-1-methyl-1H-indole-6-carboxylic acid 
• 494799-18-7 methyl 3-cyclohexyl-1H-indole-6-carboxylate 
• 494799-19-8 methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 774213-84-2 methyl 1-(2-tert-butoxy-2-oxoethyl)-3-cyclohexyl-2-phenyl-1H-indole-6-carboxylate 
• 735282-89-0 3-cyclohexyl-1-(2-morpholin-4-yl-2-oxoethyl)-2-phenyl-1H-indole-6-carboxylic acid 
• 774213-90-0 2-(6-cyano-3-cyclohexyl-2-phenyl-1H-indole-1-yl)-N,N-dimethylacetamide 
• 774213-89-7 3-cyclohexyl-1-[2-(dimethylamino)-2-oxoethyl]-2-phenyl-1H-indole-6-carboxamide 

Relevant articles and documents

Development of carboxylic acid replacements in indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase

Allosteric inhibition of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase enzyme has recently emerged as a viable strategy toward blocking replication of viral RNA in cell-based systems. We report here 2 series of indole-N-acetamides, bearing

INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to indole compounds of the formula (I): wherein R1, R2, R3, R4, A, E and X are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.

INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS

The present invention relates to indoles and azaindoles of formula (I): wherein X1, X2, X3, X4, A1, Ar1, Ar, n, p and q are as defined herein and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C virus infections.