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Benzenesulfonamide, 2,5-dimethoxy-N-3-quinolinyl-, also known as a sulfonamide derivative, is a chemical compound with a unique structure that features a benzene ring, sulfonamide group, and a quinoline moiety. It is widely used in medicinal chemistry and drug research for its potential pharmacological activities, such as antibacterial, antiviral, and antineoplastic effects. Benzenesulfonamide, 2,5-dimethoxy-N-3-quinolinylis a promising candidate for further exploration in drug development and discovery, as well as a useful intermediate in the synthesis of complex organic molecules.

496014-13-2

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496014-13-2 Usage

Uses

Used in Pharmaceutical Industry:
Benzenesulfonamide, 2,5-dimethoxy-N-3-quinolinylis used as a structural motif in the development of potential pharmaceutical agents for its potential pharmacological activities, such as antibacterial, antiviral, and antineoplastic effects.
Used in Drug Research:
Benzenesulfonamide, 2,5-dimethoxy-N-3-quinolinylis used as a promising candidate for further exploration in drug development and discovery due to its unique structure and potential pharmacological activities.
Used in Chemical Research:
Benzenesulfonamide, 2,5-dimethoxy-N-3-quinolinylis used as a useful intermediate in the synthesis of complex organic molecules, contributing to the advancement of chemical research and the development of new compounds with potential applications.

Check Digit Verification of cas no

The CAS Registry Mumber 496014-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,6,0,1 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 496014-13:
(8*4)+(7*9)+(6*6)+(5*0)+(4*1)+(3*4)+(2*1)+(1*3)=152
152 % 10 = 2
So 496014-13-2 is a valid CAS Registry Number.

496014-13-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamide

1.2 Other means of identification

Product number -
Other names 2,5-Dimethoxy-hexamethylen-bis-mercuriacetat

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:496014-13-2 SDS

496014-13-2Downstream Products

496014-13-2Relevant academic research and scientific papers

Real-time monitoring of caspase-3/8 activity by self-assembling nanofiber probes in living cells

Zhang, Li-Song,Xu, Hong-Lei,Xia, Ying,Bi, Jian-Peng,Zhang, Chuan-Zeng,Xi, Zhen,Li, Lu-Yuan,Zhang, Zhi-Song

, p. 797 - 800 (2021)

Caspase-3/8 are key members of the cysteine-aspartyl protease family with pivotal roles in apoptosis. We have designed and synthesized self-assembling probes, Nap-GFFpYDEVD-AFC and Nap-GFFpYIETD-AFC, with fluorescence 'turn-on' properties for real-time mo

Self-assembling peptide-etoposide nanofibers for overcoming multidrug resistance

Zhang, Li-Song,Yan, Li-Xin,Gao, Shan,Long, Hui,Xi, Zhen,Li, Lu-Yuan,Zhang, Zhi-Song

, p. 15321 - 15324 (2020)

We developed a new strategy to overcome the MDR of etoposide using self-assembling nanofibers. Compared with the original etoposide, the inhibitory activity of Nap-GFFpYK-etoposide1/2 against murine Lewis lung cancer or breast cancer cells was increased 10 times, and 20 times on these cells with artificially overexpressed MDR1. Our method to synthesize and separate etoposide isomers provides a new strategy for the modification of this drug. This journal is

QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF

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Paragraph 00247-00248, (2020/10/09)

Compounds and methods for their preparation and use as therapeutic or prophylactic agents, fo example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase- 1 (ENPP1).

Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP)

Dahl, Russell,Sergienko, Eduard A.,Su, Ying,Mostofi, Yalda S.,Yang, Li,Simao, Ana Maria,Narisawa, Sonoko,Brown, Brock,Mangravita-Novo, Arianna,Vicchiarelli, Michael,Smith, Layton H.,O'Neill, W. Charles,Millán, José Luis,Cosford, Nicholas D. P.

experimental part, p. 6919 - 6925 (2010/04/24)

We report the characterization and optimization of drug-like smallmolecule inhibitors of tissue-nonspecific alkaline phosphatase (TNAP), an enzyme critical for the regulation of extracellular matrix calcification during bone formation and growth.High-thro

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