4964-77-6 Usage
Uses
Used in Pharmaceutical Industry:
5,7-Dichloroquinoline is used as a building block for the development of various pharmaceutical compounds. Its unique structure allows it to be a key component in the synthesis of new drugs, contributing to advancements in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 5,7-Dichloroquinoline is utilized as a building block for the creation of agrochemicals. Its properties make it suitable for the development of compounds that can be used in agricultural applications to protect crops and enhance yields.
Used in Dye Industry:
5,7-Dichloroquinoline is used as a building block in the synthesis of dyes. Its chemical properties enable the production of a variety of dyes used in different industries, including textiles and printing.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 5,7-Dichloroquinoline plays a crucial role in the production of other organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of a wide range of organic products.
Used in Medicinal Chemistry and Drug Discovery:
Due to its unique structure and properties, 5,7-Dichloroquinoline has potential applications in medicinal chemistry and drug discovery. It may contribute to the development of new therapeutic agents and the advancement of pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 4964-77-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,6 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4964-77:
(6*4)+(5*9)+(4*6)+(3*4)+(2*7)+(1*7)=126
126 % 10 = 6
So 4964-77-6 is a valid CAS Registry Number.
4964-77-6Relevant academic research and scientific papers
Use of a readily removable auxiliary group for the synthesis of pyrrolidones by the palladium-catalyzed intramolecular amination of unactivated γ C(sp3)-H Bonds
He, Gang,Zhang, Shu-Yu,Nack, William A.,Li, Qiong,Chen, Gong
supporting information, p. 11124 - 11128 (2013/10/22)
Easy on, easy off: Directing groups found to promote the palladium-catalyzed amination of γ C(sp3)-H and C(sp 2)-H bonds of secondary amides included 5-methoxy-8-aminoquinoline, which can be removed under mild conditions (see scheme; CAN=ceric ammonium nitrate). In conjunction with a β-C-H methylation or γ-C-H arylation step, the γ-C(sp3)-H amination provided access to complex pyrrolidones from readily available precursors. Copyright
Synthesis of 5-hydroxyquinolines
Li, Jianke,Kung, Daniel W.,Griffith, David A.
scheme or table, p. 3876 - 3878 (2010/08/19)
A series of 5-hydroxyquinolines has been prepared via the Skraup reaction. Several regioisomers were made either by selective displacement of a leaving group or by using a bromo substituent as a blocking group. The bromo group was found to be an excellent blocking group due to its stability during the Skraup reaction and easy removal thereafter. Halides at the 5-position of quinoline were found to be much more reactive than those at the 7- and 8-positions. Finally, we have also found a unique method to reduce the pyridyl ring on quinolines, leaving a halogen substituent untouched.
