49642-51-5

Basic information

• Product Name: (S)-2-Methylhexanoic acid
• Synonyms: (2S)-2-Methylhexanoic acid >90%ee
• CAS NO: 49642-51-5
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.19
• Mol File: 49642-51-5.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-Methylhexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Methylhexanoic acid(49642-51-5)
• EPA Substance Registry System: (S)-2-Methylhexanoic acid(49642-51-5)

Safety Data

• Hazardous Substances Data: 49642-51-5(Hazardous Substances Data)

Usage

General Description

(S)-2-Methylhexanoic acid, also known as 2-methylcaproic acid, is a saturated fatty acid with a chemical formula of C7H14O2. It is a colorless liquid with a pungent odor, and is commonly used in the production of flavors and fragrances due to its fruity and sweaty odor. It is found naturally in some foods and is also used as a flavoring agent in the food industry. In addition, (S)-2-Methylhexanoic acid has antimicrobial properties and is used in pharmaceutical and cosmetic products as a preservative. It is also used in the synthesis of various compounds for industrial and research purposes.

Upstream product

• 102680-24-0 (R)-(-)-3-methyl-1-phenyl-1-heptene 
• 97961-66-5 (E)-2-methyl-2-hexenoic acid 
• 4536-23-6 2-methylhexanoic acid 
• 678-39-7 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol 
• 109-72-8 n-butyllithium 
• 673456-22-9 (1S,2Z)-1-({[(2S)-2-methoxy-2-phenylethoxy]methyl}(dimethyl)silyl)-1-methylbut-2-enyl acetate 
• 673456-23-0 (1S,E)-1-({[(2S)-2-methoxy-2-phenylethoxy]methyl}(dimethyl)silyl)-1-methylbut-2-enyl acetate 
• 693-04-9 butyl magnesium bromide 
• 84519-63-1 (R,E)-4-phenyl-3-buten-2-yl acetate 
• 51594-30-0 (4S)-4r-methoxymethyl-2-((Ξ)-1-methyl-pentyl)-5t-phenyl-4,5-dihydro-oxazole 
• 142-61-0 Hexanoyl chloride 
• 141022-82-4 (S)-(+)-4-isopropyl-3-hexanoyl-2-oxazolidinone 
• 542-69-8 1-iodo-butane 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 97424-48-1 (S)-1-bromo-2-methylhexane 
• 105452-95-7 (S)-2-methyl-N-phenylhexanamide 
• 13151-35-4 (S)-5-Methyldecane 
• 624-22-6 (2S)-2-methyl-1-hexanol 

Relevant articles and documents

Are Highly Stable Covalent Organic Frameworks the Key to Universal Chiral Stationary Phases for Liquid and Gas Chromatographic Separations?

High-performance liquid chromatography (HPLC) and gas chromatography (GC) over chiral stationary phases (CSPs) represent the most popular and highly applicable technology in the field of chiral separation, but there are currently no CSPs that can be used for both liquid and gas chromatography simultaneously. We demonstrate here that two olefin-linked covalent organic frameworks (COFs) featuring chiral crown ether groups can be general CSPs for extensive separation not only in GC but also in normal-phase and reversed-phase HPLC. Both COFs have the same 2D layered porous structure but channels of different sizes and display high stability under different chemical environments including water, organic solvents, acids, and bases. Chiral crown ethers are periodically aligned within the COF channels, allowing for enantioselective recognition of guest molecules through intermolecular interactions. The COF-packed HPLC and GC columns show excellent complementarity and each affords high resolution, selectivity, and durability for the separation of a wide range of racemic compounds, including amino acids, esters, lactones, amides, alcohols, aldehydes, ketones, and drugs. The resolution performances are comparable to and the versatility is superior to those of the most widely used commercial chiral columns, showing promises for practical applications. This work thus advances COFs with high stability as potential universal CSPs for chromatography that are otherwise hard or impossible to produce.

Achiral amine additives in the enantioselective hydrogenation of aliphatic α,β-unsaturated acids over cinchonidine-modified Pd/Al 2O3 catalyst

The effect of the achiral amine additive structure was studied on the enantioselective hydrogenation of (E)-2-methyl-2-butenoic acid and (E)-2-methyl-2-hexenoic acid over Pd/Al2O3 catalyst modified by cinchonidine. It was found that

Stereochemical investigations reveal the mechanism of the bacterial activation of n-alkanes without oxygen

Anaerobic growth of the bacterium strain HxN1 with n-hexane gives nearly equal amounts of (2R,1 R)- and (2S,1 R)-(1-methylpentyl)succinate, which are formed by the radical addition of the hydrocarbon to fumarate (see scheme). The highly selective attack on the pro-S hydrogen atom at C2 of n-hexane is associated with inversion of the configuration at C2 during binding to fumarate and exhibits isotopic discrimination against a C-2H bond. Copyright