4985-70-0

Usage

Uses

Used in Research Applications:
1-Chloroanthracene is used as a research compound for investigating the effects of polycyclic aromatic hydrocarbons on gap junctional intercellular communication and the activation of intracellular receptor kinase in F344 rat liver epithelial cells. This application helps in understanding the interactions and potential impacts of these chemicals on cellular processes and communication.
Used in Chemical Synthesis:
1-Chloroanthracene can be used as a starting material or intermediate in the synthesis of various organic compounds, particularly those involving polycyclic aromatic structures. Its unique chemical properties make it a valuable component in the development of new molecules with specific applications in different industries.
Used in Environmental Studies:
1-Chloroanthracene can be employed in environmental studies to understand the behavior and impact of polycyclic aromatic hydrocarbons in the environment. This knowledge can contribute to the development of strategies for pollution control and remediation efforts.
Used in Pharmaceutical Research:
Although not explicitly mentioned in the provided materials, 1-chloroanthracene may have potential applications in the pharmaceutical industry as a compound for the development of new drugs or drug candidates. Its unique chemical structure could be utilized in the design of novel therapeutic agents targeting specific biological pathways or receptors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 1914, 1986 DOI: 10.1021/jo00360a054

InChI:InChI=1/C14H9Cl/c15-14-7-3-6-12-8-10-4-1-2-5-11(10)9-13(12)14/h1-9H

Upstream product

• 56-23-5 tetrachloromethane 
• 82-44-0 1-chloroanthracene-9,10-dione 
• 4888-02-2 4-chloroanthrone 
• 79917-76-3 N-(4-Chloro-anthracen-9-yl)-formamide 
• 77287-34-4 formamide 
• 7664-41-7 ammonia 
• 6406-96-8 1,5-dichloroanthracene 

Downstream Products

• 3752-42-9 anthracene-1-carbonitrile 
• 610-50-4 1-hydroxyanthracene 
• 10035-10-6 hydrogen bromide 
• 1171-95-5 1-anthryldiphenyl-phosphine 
• 120-12-7 anthracene 
• 64819-61-0 1-isopropylanthracene 
• 66291-35-8 1-ethylanthracene 
• 1079-71-6 1,2,3,4,5,6,7,8-octahydroanthracene 
• 613-31-0 9,10-dihydroanthracene 
• 2141-42-6 1,2,3,4-tetrahydroanthracene 
• 33188-82-8 1-chlorotriptycene 
• 22980-71-8 8,10-dichloroanthracene 
• 195-06-2 Dibenzophenanthren 

Relevant academic research and scientific papers

Efficient indium-mediated dehalogenation of aromatics in ionic liquid media

An efficient indium-mediated dehalogenation reaction of haloaromatics and haloheteroaromatics in ionic liquids has been studied. This method is simple and effective in the presence of [bmim]Br. Furthermore, this methodology is environmentally friendly compared with conventional ones.

Syntheses and Absolute Stereochemistry of Chiral 9,10-Dihydro-9,10-ethanoanthracenes and their Tricarbonylchromium Complexes

Several chiral mono- and disubstituted 9,10-dihydro-9,10-ethanoanthracenes have been prepared from the corresponding anthracenes.Most of them were separated into enantiomers by chromatography on cellulose triacetate (CTA) and their absolute chiralities established by chiroptical comparison (via their CD spectra) with key compounds of known configuration.From the laevorotatory 1,5-dibromo derivative 16 the dextrorotatory dideuterio hydrocarbon (+)(9S,10S)-20 was obtained.Complexation of 2,6-dimethyl 9,10-dihydro-9,10-ethanoanthracene (+)-25, obtained by enantioselective chromatography on CTA , with Cr(CO)6 afforded two mono tricarbonylchromium complexes as well as the bis-exo,endo-complex (+)-28.Configurational assignments (exo,endo) are based on the absorption patterns of the bridge protons in the 1H NMR spectra. Keywords: (+)-1,5-Dideuterio-9,10-dihydro-9,10-ethanoanthracene; Enantioselective chromatography on CTA; Circular dichroism; Configurational correlation; Tricarbonylchromium complexes.

Benzannulated Isobenzofurans

A number of arynes, generated by treatment of haloarenes with sodium or potassium amide in tetrahydrofuran, were trapped with furan.The resulting dihydro epoxy arenes were converted into the following annulated isobenzofuran derivatives by using reverse Diels-Alder methodology: naphthofuran, phenanthrofuran, pyrenofuran, pyrenofuran, anthrafuran, phenanthrofuran and phenathrofuran.Bimolecular rate constants for the addition of maleic anhydride to these furans were measured, and were correlated with the Herndon structure count.Addition of arynes to selected members of this furan series yielded adducts which were deoxygenated to afford polycyclic aromatic hydrocarbons.

Sulfonation of aromatic compounds in the presence of solvents

A process for the sulfonation of aromatic compounds wherein an aromatic substance consisting of one or more aromatic compounds susceptible to the action of sulfur trioxide is formed into a reactant by admixture with one or more organic liquids, substantially inert to sulfur trioxide under the conditions of the process, which reactant is brought to boiling at a temperature not greater than 100° C under a pressure of from 0.1 mm Hg to atmospheric pressure, gaseous sulfur trioxide is introduced thereinto thereby causing it to continue to boil, the component or components of the reactant thus volatilized is or are reconverted to liquid in a heat-exchanger and recycled to the reaction chamber, and the pressure in the reaction chamber and the rate at which the gaseous sulfur trioxide is introduced into the reactant are controlled so as to ensure that there is always present in the reaction chamber an amount of volatilizable matter exceeding that amount volatilizable by the heat of reaction of the aromatic substance present in the reaction chamber with the gaseous sulfur trioxide in contact with said aromatic substance and that the temperature of the reaction mixture is a temperature of 100° C or below.