50-38-4Relevant articles and documents
Preparation method of 2, 3, 5, 6-tetrachlorobenzoyl chloride
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Paragraph 0040-0043; 0040; 0044; 0047-0054, (2020/10/04)
The invention discloses a preparation method of 2, 3, 5, 6-tetrachlorobenzoyl chloride, and relates to the field of organic synthesis. The preparation method comprises the following steps of: synthesizing pentachlorobenzene serving as a raw material and m
Carboxylation of C-H bonds using N -heterocyclic carbene gold(I) complexes
Boogaerts, Ine I. F.,Nolan, Steven P.
supporting information; experimental part, p. 8858 - 8859 (2010/08/21)
A highly efficient [(NHC)AuI]-based (NHC = N-heterocyclic carbene) catalytic system for the carboxylation of aromatic and heteroaromatic C-H bonds was developed. The significant base strength of the Au-OH species is at the origin of the activation process and permits the facile functionalization of C-H bonds without the use of other organometallic reagents.
THE PREPARATION AND SOME REACTIONS OF 2,3,5,6-TETRACHLOROPHENYLMAGNESIUM CHLORIDE
Rahman, M. T.
, p. 25 - 30 (2007/10/02)
The reaction of pentachlorobenzene with metallic magnesium in THF at 10-15 deg C gives after hydrolysis 1,2,4,5-tetrachlorobenzene (76percent) and pentachlorobenzene (8percent); after trimethylsilylation, 1,2,4,5-tetrachloro-3-(trimethylsilyl)benzene (74percent), pentachloro(trimethylsilyl)benzene (8percent) and 1,2,4,5-tetrachlorobenzene (6percent); after iodination, 1,2,4,5-tetrachloroiodobenzene (44percent), pentachloroiodobenzene (12percent) and 1,2,4,5-tetrachlorobenzene (9percent); and finally after carbonation, 2,3,5,6-tetrachlorobenzoic acid (58percent).These products indicate that in the Grignard reaction a mixture of largely 2,3,5,6-tetrachlorophenylmagnesium chloride and some pentachlorophenylmagnesium chloride is formed.The formation of pentachlorophenylmagnesium chloride is explained on the basis of metal-hydrogen exchange reaction between 2,3,5,6-tetrachlorophenylmagnesium chloride and the unreacted pentachlorobenzene.