5009-92-7Relevant academic research and scientific papers
IONIC ALKYLATION OF TERTIARY ALKYL HALIDES WITH TETRAALKYLSILANES
Bolestova, G. I.,Parnes, Z. N.
, p. 32 - 36 (2007/10/02)
In the reaction of tertiary alkyl halides with tetraethyl-, tetrapropyl-, tetrabutyl-, and tetraamylsilane in the presence of AlX3 the halogen atom is substituted by the alkyl group with the formation of the corresponding saturated hydrocarbons containing a quaternary carbon atom.As a result of the hydride mobility of the β-hydrogen atom in the tetraalkylsilane ionic hydrogenolysis of the substrate occurs in addition to alkylation, and the degree of hydrogenolysis depends on the alkyl substituent in the silane.
Direct Geminal Dimethylation of Ketones using Dimethyltitanium Dichloride
Reetz, Manfred T.,Westermann, Juergen,Steinbach, Rainer
, p. 237 - 239 (2007/10/02)
Ketones are readily converted into the corresponding geminal dimethyl derivatives on reaction with dimethyltitanium dichloride under mild conditions; tertiary alcohols react similarly.
Efficient Coupling of Tertiary Alkyl Halides with Dialkylzinc and Titanium Compounds
Reetz, Manfred T.,Wenderoth, Bernd,Peter, Roland,Steinbach, Rainer,Westermann, Juergen
, p. 1202 - 1204 (2007/10/02)
Dialkylzinc compounds react with tertiary halides to afford the corresponding coupling products containing a quaternary carbon atom, thereby making geminal dialkylation of ketones or hydroalkylation of olefins possible.
