501084-86-2Relevant academic research and scientific papers
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri, Achyutharao,Tilley, Jefferson W,Lou, Jian Ping,Chen,Kaplan, Gerry,Mennona, Frank,Campbell, Robert,Guthrie, Robert,Huang, Tai-Nan,Rowan, Karen,Schwinge, Virginia,Renzetti, Louis M
, p. 2479 - 2482 (2007/10/03)
A series of N-benzoyl-4-[(2,6-dichlorobenzoyl)amino]-L-phenylalanine derivatives was prepared in order to optimize the substitution on the N-benzoyl moiety for VCAM/VLA-4 antagonist activity. Disubstitution in the 2- and 6-positions is favored and a range
