676345-24-7

Upstream product

• 503271-69-0 6-amino-2-[[(2,3-difluorophenyl)methyl]thio]-4(3H)-pyrimidinone 
• 333-20-0 potassium thioacyanate 
• 503271-69-0 6-amino-2-[[(2,3-difluorophenyl)methyl]thio]-4-pyrimidinol 

Downstream Products

• 259100-41-9 2-amino-5-(2,3-difluoro-benzylsulfanyl)-thiazolo[4,5-d]pyrimidin-7-ol 
• 676345-69-0 5-[((2,3-difluorophenyl)methyl)thio]-7-{[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino}thiazolo[4,5-d]pyrimidin-2(3H)-one 
• 676345-71-4 2-({2-chloro-5-[((2,3-difluorophenyl)methyl)thio]thiazolo[4,5-d]pyrimidin-7-yl}amino)-(2S,3S)-butane-1,3-diol 
• 259103-43-0 7-chloro-5-[(2,3-difluorobenzyl)sulfanyl][1,3]thiazolo[4,5-d]pyrimidin-2-amine 
• 259100-41-9 2-amino-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-7(6H)-one 

Relevant academic research and scientific papers

Evaluation of a series of bicyclic CXCR2 antagonists

The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat

NOVEL COMPOUND

A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof for use in therapy.

NOVEL COMPOUND

A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof for use in therapy.