503603-89-2

Upstream product

• 181941-65-1 ethyl 1-{(3S)-1-[(S)-1-phenylethyl]-5-thioxopyrrolidin-3-yl}cyclopropanecarboxylate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 181941-62-8 ethyl (E)-3-(1-ethoxycarbonylcyclopropan-1-yl)-2-butenoate 
• 181941-61-7 ethyl 3-(1-ethoxycarbonylcyclopropan-1-yl)-3-hydroxybutanoate 
• 181941-63-9 ethyl 1-{5-oxo-1-[(S)-1-phenylethyl]-2,5-dihydro-1H-pyrrol-3-yl}cyclopropanecarboxylate 
• 190954-59-7 ethyl 1-{(3S)-5-oxo-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 

Downstream Products

• 503603-90-5 ethyl 1-[(3S)-1-benzyloxycarbonylpyrrolidin-3-yl]cyclopropanecarboxylate 
• 503603-91-6 1-[(3S)-1-benzyloxycarbonylpyrrolidin-3-yl]cyclopropanecarboxylic acid 
• 181941-59-3 (3R)-1-benzyloxycarbonyl-3-[1-(tert-butoxycarbonylamino)cyclopropan-1-yl]pyrrolidine 

Relevant academic research and scientific papers

Synthesis and structure - Activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8- methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents

A series of novel 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolones bearing fluorinated (3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl substituents at the C-7 position (2-4) was synthesized to obtain potent drugs for infections cau