505-86-2Relevant articles and documents
Simple process for the preparation of cetyltrimethylammonium naproxenate (naprocet)
Bolchi, Cristiano,Valoti, Ermanno,Fumagalli, Laura,Ruggeri, Paola,Straniero, Valentina,Pallavicini, Marco
, p. 976 - 979 (2014)
Specifications for cetyltrimethylammonium (CTA) naproxenate (naprocet), the active ingredient of pharmaceutical liquid preparations used as antiseptic-antinflammatory detergents, fix severe limits to the presence of residual inorganic counteranion deriving from the starting CTA salt. A new simple procedure, which avoids ionic exchange chromatography and utilizes CTAHSO4 in place of CTABr and CTACl, exploits the quantitative precipitation of K2SO4 from methanol to yield naprocet in line with such specification requirements.
Counter cation dependent and stimuli responsive supramolecular polymers constructed by calix[4]pyrrole based host–guest interactions
Yuvayapan, Samet,Aydogan, Abdullah
, p. 633 - 639 (2019)
Carboxylate tethered calix[4]pyrroles in the form of their tetrabutylammonium (TBA) and cetyltrimethylammonium (CTA) salts were synthesized via an acid base reaction between the corresponding carboxylic acid functionalized calix[4]pyrrole and tetrabutyl-or cetyltrimethylammonium hydroxide. The host–guest recognition motif based on these calix[4]pyrrole macrocycles and tethered carboxylate units was employed to construct novel A–B type supramolecular polymers from low molecular weight monomers in chloroform. These supramolecular polymers were found to be dependent on the counter cation in terms of the properties of supramolecular polymers.1H-, DOSY-, NOESY-NMR spectroscopic analyses, viscosity measurements, and SEM results were used to characterize supramolecular polymers and revealed that the CTA cation becomes a direct part of supramolecular polymer via cation–π interactions between the ammonium part of CTA and carboxylate-bound calix[4]pyrrole, effecting the overall properties of supramolecular polymers such as viscosity, gel formation, and drawing fibers. Additionally, reversible pH-and thermo-responsiveness of the supramolecular polymers were demonstrated for the first time for an anion recognition induced calix[4]pyrrole based supramolecular polymer.
Synthesis of two chiral surfactants by a simple method and the surface activity evaluation
Bai, Yun,Chen, Gang,Dong, Sanbao,Liu, Dengwei,Qu, Chengtun,Yan, Jiao,Zhang, Jie,Zhu, Shidong
, (2020)
In order to expand the application range of surfactants, two chiral surfactants named CTACYT and CTATYS were synthesized by reacting cetyltrimethylammonium chloride (CTAC) with L-cysteine and L-tyrosine, respectively by a simple method. Studies show that the foaming ability, foam stability and emulsifying properties of both CTACYT and CTATYS are superior to CTAC. The corrosion inhibition efficiencies of CTACYT and CTATYS are 96.72% and 90.22%, respectively, which are higher than that of CTAC. The new chiral surfactants remain the chiral character, and the specific optical rotations of CTACYT and CTATYS were 8.1° and 11.6°, respectively. This work provides a new and easy way to the synthesis of chiral surfactants, which will benefit the related research in this field.
Preparation of Acifluorfen-Based Ionic Liquids with Fluorescent Properties for Enhancing Biological Activities and Reducing the Risk to the Aquatic Environment
Cao, Yongsong,Li, Jianqiang,Niu, Junfan,Tang, Gang,Tang, Jingyue,Tang, Rong,Yang, Jiale,Zhang, Wenbing,Zhou, Zhiyuan
, p. 6048 - 6057 (2020/06/26)
In this work, 12 novel herbicidal ionic liquids (HILs) based on acifluorfen were prepared by pairing with the fluorescent hydrazides or different alkyl chains for increasing activities and reducing negative impacts on the aquatic environment. The results showed that the fluorescence of coumarin hydrazide in the HILs was applied as the internal and supplementary light source to meet the requirement of light wavelength range of acifluorfen, which improved the phytotoxicity of acifluorfen to weeds by enhancing singlet oxygen generation with increased sunlight utilization. The herbicidal activities of HILs were related positively with the length of chain of cation under high light intensity and depended mainly on the fluorescence characteristic of the cation under low light intensity, and the double salt IL forms of acifluorfen containing coumarin hydrazide and n-hexadecyltrimethylammonium had enhanced efficacies against broadleaf weeds in the field. Compared with acifluorfen sodium, HILs had lower water solubility, better surface activity, weaker mobility in soils, and higher decomposition temperature. These results demonstrated that HILs containing different cations provided a wider scope for fine-tuning of the physicochemical and biological properties of herbicides and established a promising way for the development of environmentally friendly herbicidal formulations.
