505097-32-5

Upstream product

• 105-36-2 ethyl bromoacetate 
• 505097-31-4 3-[6-(4-ethylphenyl)-2-methylpyrrolo[1,2-b]pyridazin-7-yl]-1,6-dihydro-6-pyridazinone 
• 2632-14-6 4-ethylphenacyl bromide 
• 505097-26-7 7-(6-chloro-3-pyridazinyl)-6-(4-ethylphenyl)-2-methylpyrrolo[1,2-b]pyridazine 
• 505097-16-5 6-(4-ethylphenyl)-2-methylpyrrolo[1,2-b]pyridazine 
• 1632-74-2 3,6-dimethylpyridazine 

Relevant academic research and scientific papers

Regioselective aluminium chloride induced heteroarylation of pyrrolo[1,2-b]pyridazines: Its scope and application

We describe a detailed study on the novel synthesis of 6,7-disubstituted pyrrolo[1,2-b]pyridazines through AlCl3 induced C-C bond formation reactions. A wide variety of 6-aryl substituted azolopyridazines was reacted with 3,6-dichloropyridazine to give 7-pyridazinyl substituted pyrrolopyridazines regioselectively in good to excellent yield. The mechanism and regiochemistry of the reaction along with applications of the methodology are discussed.